background: hypoalbuminemia may be caused by liver disease, nephrotic syndrome, burns, protein-losing entropathy, malnutrition, and metabolic stress. alterations in albumin in metabolic stress such as cardiac surgery have been previously investigated. we studied serum albumin concentration in children with congenital heart disease and also the association of hypoalbuminemia with mortality and m...

introduction : albumin, one of the most important plasma proteins, has a difficult process of synthesis and production. we compared two different methods for albumin purification: carboxymethyl cellulose (cm cellulose) resin exchange and diethylaminoethyl cellulose (deae cellulose) resin exchange in order to determine which resin could be more beneficial. materials and methods : two ion exchang...

dietary flavonoids show beneficial effects in the prevention of chronic diseases. however, flavonoid bioavailability is poor, probably due to their interaction with serum albumins. in the current work, the binding interactions of eight related flavonoids, sharing a similar core structure, with bovine serum albumin (bsa) were investigated by fluorescence spectroscopy. the binding affinities of t...

patients and methods this prospective cohort study was performed on 90 diabetic type 2 patients with microalbuminuria, who were selected according to the consecutive sample selection method during 6 years. data were collected through regular and systematic measurements of serum albumin as the response variable and body mass index, systolic and diastolic blood pressure, the duration of diabetes,...

albumin has a fundamental role in human body. its main tasks in blood are to regulate osmotic blood pressure, maintaining the ph, and transporting metabolites and drugs throughout the vascular system.  pharmacological studies of the interaction of drugs on hsa are important due to structural and functional changes of this vital protein; thus, here in this research the effect of valproate as a c...

 Background: Inflammatory process has a substantial contribution in the development of anemia in chronic hemodialysis patients. Low serum albumin in hemodialysis patients is considered a marker of inflammation. The present longitudinal study aimed to determine the relationship between low baseline serum albumin and future development of anemia. Methods: The population of this study consiste...

objective: to evaluate the capability of ascitic fluid dipstick results for ph, glucose, and protein in order to predict a low serum-ascites albumin gradient (saag) at the bedside of the patient in the emergency department (ed). methods: this prospective cross-sectional study was conducted during one year in the ed of afzalipour hospital in kerman, iran. all patients with diagnostic or therapeu...

human serum albumin (hsa) is an important protein that carries variety of substances like some hormones and drugs in blood. pharmacological studies of the interaction of many drugs and hsa are reported during several decades, specially recently years. interaction of cortisol and fluoxetine hydrochloride (flx) (as a common anti-stress drug) with hsa (as their carrier in blood) has been studied s...