Background Beta-thalassemia patients receive blood products from blood transfusion centers repeatedly. Blood transfusion can transmit Cytomegalovirus (CMV) and Toxoplasma gondii. The aim of this study was serological evaluation of these two infectious agents in thalassemia patients. Materials and Methods In a cross-sectional study, the enzymelinked immunosorbent assay (ELISA) testing was pe...

368 blood and Carcass randomly sampled from slaughtered animals for detection Toxoplasmosis. The blood samples were examined for existence Infection by serological method (Dye test) and the tissue samples from different parts of carcass including skeletal muscle, diaphragm, heart, liver and lymphnode, which ground in an electric grinder and digested by pepsin. Bioassay technique and inoculated...

Sera from 23 proven or clinically suspected cases of Pneumocystis carinii pneumonitis (PCP) in immunosuppressed patients predominantly with acute lymphoblastic leukaemia, and from 91 normal people, were examined for antibody to P. carinii by indirect immunofluorescence. Low levels of antibody were found in 51 of 91 normal people and elevated or rising titres of antibody in 18 out of 21 cases fr...

Leptospirosis is a zoonotic disease caused by spirochetes of the genus Leptospira. 1,2 Leptospirosis affects human beings and many other species of vertebrates, it can present in a wild spectrum of clinical manifestations in human being. 3 Many wild and domestic animals are reservoirs for leptospira organisms and they shed these organisms in their urine thereby contaminating fresh water, mud an...

New insight into the immunological function of the thymus has added to the significance of the rare primary neoplasms of this organ. It has long been known that thymomas are associated with a high incidence of certain systemic diseases, the best recognized of which are myasthenia gravis (Castleman, 1955), pure red-cell aplasia (Havard and Scott, 1960), and hypo-y-globulinaemia (Gafni, Michaeli,...

OBJECTIVE The aims of this study were to describe the clinical presentation of primary SS (pSS) in a large cohort of patients by assessing the prevalence of the patient subgroups at high risk for severe extraglandular manifestations and to explore the influence of the patients' serological profile on disease severity and on immunosuppressive drug utilization. METHODS Cumulative demographic, c...

background: brucellosis is one of the endemic and a zoonotic disease of the iran. science the rapid diagnosis and quick treatment are very important, selection of a sensitive and specific test solving this problem is of a great importance. the main aim of this study is comparison of routine serologic test with standard elisa test. materials and methods: in this survey, 176 suspected patients wi...

Inherited complement deficiencies are associated with a variety of connective tissue diseases. A family with inherited deficiency of complement factor 2 (C2) is described in which two family members with homozygous C2 deficiency developed cutaneous vasculitis and siccasyndrome. The otherfamily members had heterozygous C2 deficiency and each member had the HLA-A25, B18, DR2 (w15) haplotype. The ...

BACKGROUND Some syphilis patients remain in a serologically active state after the recommended therapy. We currently know too little about the characteristics of this serological response. METHODS We conducted a cohort study using the clinical database from Zhongshan Hospital, Medical College of Xiamen. In total, 1,327 HIV-negative patients with primary, secondary, latent, and tertiary syphil...