No large studies of cardiovascular syphilis at necropsy have been reported since 1964. We examined at necropsy 90 patients who had characteristic morphologic findings of syphilitic aortitis. None had ever undergone cardiovascular surgery. With the exception of 2 cases seen more recently, the hearts and aortas of the 90 patients were examined and categorized by one of us (W.C.R.) from 1966 to 19...

BACKGROUND Serologic testing for herpes simplex virus type-2 (HSV-2) is being implemented in sexually transmitted disease (STD) clinics. GOAL To determine the performance characteristics of two HSV-2 type-specific serologic assays in a public health laboratory. STUDY DESIGN Sera stored from a cross-sectional study were tested with the Meridian Diagnostics and Focus Technologies HSV-2 ELISA ...

The new system HEPAXPERT-IIIIWWW an implementation of HEPAXPERT -III' for WWW is an expert system that interprets the results of qualitative and quantitative routine serologic tests for infection with hepatitis A and B. The fully interactive system based on Cold Fusion Application Servertm is the successor of an off-line HEPAXPERT/WWW2 that returned the results by e-mail up to 24 hours after re...

Hepatitis E — Continued Outbreaks of hepatitis E (i.e., enterically transmitted non-A, non-B hepatitis) have occurred in some parts of the world and have generally been related to contaminated water supplies. Until recently, when research-based serologic tests ( 1,2 ) were developed to test for antibody to hepatitis E virus (anti-HEV), no serologic test was available to identify HEV infection, ...

BACKGROUND The purpose of this study was to estimate the cost-effectiveness of using individual-donor nucleic acid testing (ID-NAT) in addition to serologic tests compared with the sole use of serologic tests for the identification of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) among blood donors in Sweden. STUDY DESIGN AND METHODS The two strategi...

Prevalence of antibodies to Neospora caninum was determined in a cross-sectional consensus survey of 1029 bovines in a dairy herd with endemic Neospora-induced abortion. Sera were screened by indirect fluorescent antibody test (IFAT). The prevalence of N. caninum antibody in the IFAT was 17.9% in 107 neonates, 26.2% in 233 yearling heifers and steers, 39.07% in 218 mature heifers, and 26.9% in ...

The serodiagnosis of human psittacosis was considerably improved by a microimmunofluorescence (MIF) assay that uses selected strains of Chlamydia psittaci, C. pneumoniae, and C. trachomatis as antigens. The 78 patients examined in the study were clinically diagnosed as having psittacosis on the basis of compatible clinical symptoms following exposure to sick birds. The conventional complement f...