sepsis is a significant cause of morbidity and mortality in neonates. the most common pathogens of bacterial sepsis and antibiotic sensitivity patterns vary in different parts of the world. the aim of this study was to determine the most common pathogens and outcome of neonatal sepsis and also antibiotic sensitivity patterns of klebsiella species. a retrospective descriptive study was carried o...

introduction melioidosis is a rapidly fatal infectious disease caused by burkholderia pseudomallei, an agent of potential biothreat, endemic in several parts of india. most melioidosis-induced infected aneurysms are located in the abdominal or thoracic aorta. case presentation we reported two unusual cases of melioidosis resulting in pseudoaneurysm of the descending thoracic aorta. in both case...

Background: Introduction: Searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. There are many biomarkers reported for neonatal sepsis. Haptoglobin is an acute phase reactants which rise in response to infection and injuries. In this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

background: serum procalcitonin (pct) levels differ in patients with bacterial or fungal infections and are significantly elevated in patients with gram-negative bacteremia. we evaluated the diagnostic accuracy of different inflammatory markers to discriminate sepsis caused by different pathogens. materials and methods: we included 328 episodes of bacteremia from 292 patients with sepsis and 31...

Background: Early detection of neonatal sepsis and categorization of patients based on clinical severity is not yet effectively achieved. Some hematological parameters are used to formulate a hematological scoring system (HSS) and a modified hematological scoring system (MHSS) to diagnose neonatal sepsis. A promising biomarker: Presepsin, or Soluble Cluster of Differentiation 14 SubType (sCD14-...

sepsis is the systemic response to severe infection in critically ill patients. sepsis, septic syndrome & septic shock represent the increasingly severe stages of the same disease. despite the remarkable improvements in outcome, sepsis & septic shock remain an important cause of morbidity & mortality in children. this is a retrospective study among the patients who were admitted in the pediatri...

sepsis is a systemic inflammatory response to infection. sepsis, which can lead to severe sepsis, septic shock, and multiple organ dysfunction syndrome, is an important cause of mortality. pathogenesis is extremely complex. in recent years, cell hypoxia caused by mitochondrial dysfunction has become a hot research field. sepsis damages the structure and function of mitochondria,conversely, mito...

septicemia in neonates is the commonest cause of mortality. early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. the laboratory criteria are often non specific and not fully reliable. the objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. we searched pubmed...

Background Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) in the setting of fever. This study aimed to evaluate the prevalence, pathogen distribution, antibiotic resistance pattern and the most common clinical features in infants with suspected sepsis admitted to teaching hospitals of Ilam, Ir...