BACKGROUND Neuraxial anaesthesia produces a sedative and anaesthetic-sparing effect. Recent evidence suggests that spinal cord anaesthesia modifies reticulo-thalamo-cortical arousal by decreasing afferent sensory transmission. We hypothesized that epidural anaesthesia produces sensory deafferentation-dependent sedation that is associated with impairment of brainstem transmission. We used brains...

Background: Various studies have investigated the role of different drugs as adjuncts to SBPB to prolong the duration and quality of analgesia without producing any major adverse effects. We conducted a study to compare the novel alpha 2 agonists (clonidine and dexmedetomidine) with respect to onset, duration of block and postoperative analgesia when added as adjuvants to the local anesthetic 0...

conclusions dexmedetomidine added to bupivacaine in spinal anesthesia is more effective to increase duration of block, providing more appropriate sedation and less postoperative pain scale and post-operative nausea and vomiting (ponv) compared to fentanyl additive. results totally, 84 patients were randomly divided into three groups of 28 patients. onset of sensory block in dex group was signif...

aim and background:   intravenous regional anesthesia is easy to administer, reliable, and costeffective methods and materials:   in a randomized, double blinded, clinical trial thirty patients of 18 to 60 findings:   sensory block onset time, motor block onset time, tourniquet pain and analgesic conclusions:   addition of nitroglycerine to lidocaine to intravenous regional anesthesia can

Background: There are different anesthetic techniques for AVF (Arterio-venous fistula) creation as general anesthesia, regional anesthesia and local anesthetic infiltration. Sympathetic nerve block is produced by regional anesthesia which increases intraoperative venous diameter and vessel flow, both intra-operatively and for several hours post-operatively. Regional anesthesia can maintain adeq...

BACKGROUND AND OBJECTIVES Success rate of catheter applications is low in supraclavicular block. Thus, bupivacaine and levobupivacaine become important with their long effect time in single injection practices. In this study, we aimed to compare the effectiveness, side effects and complications of bupivacaine and levobupivacaine in supraclavicular block. METHODS Sixty patients aged between 20...

Objectives: Alpha-2-receptor agonist has been used as an additive to local anaesthetics for various regional anaesthetic techniques. We compared clonidine and dexmedetomidine as an adjuvant to local anaesthetic agent in ultrasound guided axillary brachial plexus block with respect to hemodynamic parameters, onset and duration of sensory, motor block and duration of analgesia. Methods: Ultrasoun...