We have examined the effects of commercially available preparations and drug-free solvents of diazepam (Valium, Diazepam-Lipuro) and midazolam (Dormicum) by N-formylmethionyl-leucylphenylalanine (FMLP)- and zymosan-induced polymorphonuclear cell (PMN) chemiluminescence and in a cell-free chemiluminescence system. In the case of Valium, drug-free solvent and diazepam suppressed PMN chemiluminesc...

Objective: Inflammation is one of the major components of asthma. Our aim was to evaluate the effects of C. sativus extract on total and differential white blood cells (WBC) count in lung lavage fluid (LLF) of ovalbumin-sensitized rats. Materials and Methods: Forty rats were divided into five groups (n = 8 for each group) as control (C), sensitized with injection and inhalation of ovalbumin (OA...

We describe a novel platform technology for both significantly enhancing and obtaining chemiluminescence signatures "on-demand", subsequently named Microwave-Triggered Metal-Enhanced Chemiluminescence. By combining the use of silver nanoparticles to plasmon enhance chemiluminescence with the use of low power microwaves to localize heating around the nanostructures, we can both optically amplify...

Luminol-mediated chemiluminescence in neutrophils is stimulated by Sendai virus and by influenza virus; Lettré cells also exhibit chemiluminescence (less than 10% of that of neutrophils), which is stimulated by Sendai virus and by influenza virus. Virally induced permeability changes are not responsible for chemiluminescence, since (i) extracellular Ca2+ inhibits permeability changes but stimul...

Objective: Asthma is a chronic inflammatory disease of the respiratory airways distinguished by edema and infiltration of inflammatory immune cells. To test our hypothesis about the anti-inflammatory effect of saffron, we examined effects of Crocus sativus (C. sativus) extract as a prophylactic anti-inflammatory agent in sensitized rats. Materials and Methods: To induce experimental asthma, rat...

a sensitive fluorometric method for the determination of deferiprone (dfp) based on the formation of a luminescent complex with tb3+ ions in aqueous solutions is reported. the maximum excitation and emission wavelengths were 295 and 545 nm, respectively. the effects of various factors on the luminescence intensity of the system were investigated and optimized, then under the optimum conditions,...

objective: the effects of natural adjuvants were examined on total and differential wbc counts in lung lavage of sensitized guinea pigs. materials and methods: in three sensitized groups of guinea pigs including: untreated sensitized animals (s), sensitized animals treated with adjuvant g2 (s+g2) and g2f (s+g2f) as well as non-sensitized group (c) (n=6 for each group), total and differential wb...

a chemiluminescence (cl) method has been developed for the determination of hydroxyzine (hyd) and its metabolite cetirizine (cet). the method is based on sensitizing effect of cet and hyd on the weak cl reaction between ru(phen)32+ and acidic ce(iv). a mechanism for the cl reaction has been proposed on the basis of uv-vis, fluorescent and cl spectra. by using the recommended procedure, the cali...