نتایج جستجو برای: selective beta

تعداد نتایج: 380601  

Journal: :jundishapur journal of microbiology 0
zohre ghanavi institute of standard and industrial research of iran, tehran, ir iran; institute of standard and industrial research of iran, tehran, ir iran. tel: +98-9125817046, fax: +98-2122431598 saeed mollayi young researchers and elites club, north tehran branch, islamic azad university, tehran, ir iran; young researches and elites club, north tehran branch, islamic azad university, tehran, ir iran, tel: +98-2122431598, fax: +98-2122431598 zahra eslami medicinal plants and drug research institute, shahid beheshti university tehran, iran

materials and methods samples were collected from six different farms and milk factories in iran, and were tested by beta-star and cylinder-plate methods. results among 992 raw milk samples, 236 positive samples, 9 suspected and 747 negative samples in respond to beta-star test and among 236 samples, which had positive responses to beta-star test, 28 positive, 0 suspected and 208 negative resul...

Journal: :Cancer research 2001
V Vivat-Hannah D You C Rizzo J P Daris P Lapointe F C Zusi A Marinier M V Lorenzi M M Gottardis

The focus of this study was to develop retinoic acid receptor (RAR) RAR alpha/beta selective agonists with anticancer efficacy and reduced toxicity associated with RAR gamma activity. In these studies, we report the identification and characterization of high-affinity RAR alpha/beta selective agonists with limited RAR gamma activity. These compounds inhibited human tumor cell line proliferation...

Journal: :Investigative ophthalmology & visual science 1981
B K Colasanti R R Trotter

Ocular tension of cats was measured after topical administration of the selective beta 1-adrenergic agonist CGP 7760B, the selective beta 1-adrenergic antagonist atenolol, the selective beta 2-adrenergic agonist salbutamol, the selective beta 2-adrenergic antagonist H 35/25, and the mixed beta 1- and beta 2-adrenergic antagonist timolol. Although atenolol did not alter intraocular pressure, CGP...

2017
Mette Reilev Per Damkier Lotte Rasmussen Morten Olesen Martin Thomsen Ernst Rikke Mie Rishøj Morten Rix Hansen Anne Broe Alexander Steenberg Dastrup Maja Hellfritzsch Sidsel Arnspang Anton Pottegård Jesper Hallas

Background Some studies indicate a reduced risk of serious upper gastrointestinal bleeding (UGIB) for users of beta-blockers, but the association remains to be confirmed in larger studies and characterized with respect to differences among beta-blockers. We aimed to assess whether beta-blocker use decreases the risk of UGIB. Methods We conducted a register-based, population-based case-control...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2007
Helen Pui Shan Wong Le Yu Emily Kai Yee Lam Emily Kin Ki Tai William Ka Kei Wu Chi-Hin Cho

Cigarette smoking is a putative environmental risk factor for colon cancer. Nicotine, an active alkaloid in tobacco, has been implicated in carcinogenesis. In the present study, we demonstrated that oral nicotine administration (50 or 200 microg/ml) for 25 days stimulated growth of human colon cancer xenograft in nude mice. It also increased vascularization in the tumors and elevated cotinine a...

Journal: :The Journal of pharmacology and experimental therapeutics 2002
Lance R McMahon Lisa R Gerak Lawrence Carter Chunrong Ma James M Cook Charles P France

Drug discrimination was used to examine the effects of benzodiazepine (BZ)(1) receptor-selective ligands in rhesus monkeys. In diazepam-treated (5.6 mg/kg, p.o.) monkeys discriminating the nonselective BZ antagonist flumazenil (0.32 mg/kg, s.c.), the BZ(1)-selective antagonist beta-carboline-3-carboxylate-t-butyl ester (beta-CCt) substituted for flumazenil. The onset of action of beta-CCt was d...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید بهشتی 1356

چکیده ندارد.

Journal: :Molecular pharmacology 1998
H Kikkawa M Isogaya T Nagao H Kurose

To determine the structural basis for binding subtype selective agonists in the beta-adrenergic receptor (beta AR), we examined the interaction of the mutant beta 2AR and chimeric beta 1/beta 2AR with a selective beta 2AR agonist, TA-2005 (8-hydroxy-5-[(1R)-1-hydroxy-2-[N-[(1R)-2-(p-methoxyphenyl)-1-methyle thy l] amino]ethyl] carbostyril hydrochloride). The beta 2AR mutant with Ala substitute...

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