The concept of "normalized velocity" has been applied in this study to the echocardiographic (echo) assessment of left ventricular (LV) function in 87 patients. The following normalized velocities were calculated from the ultrasound recording of LV wall motion: 1) the mean circumferential fiber shortening rate (mean VCF), 2) the mean normalized posterior wall velocity (Vpw), and 3) the mean nor...

Spinning extrusion forming (SEF) is a type of rheologic process for making complex structured aerospace components, such as ribbed cylindric shells. However, our understanding the texture evolution and recrystallization behavior during SEF still limited, especially in system like 2195 Al–Li alloy, which considered to be ideal material candidate vehicles because its low density high specific str...

Sclerosing epithelioid fibrosarcoma (SEF) is a rare soft tissue sarcoma mostly occurring in extraosseous sites. SEF represents a clinically challenging entity especially because no standardized treatment regimens are available. Intraosseous localization is an additional challenge with respect to the therapeutical approach. We report on a 16-year-old patient with SEF of the right proximal tibia....

The functional organization of the low-threshold supplementary eye field (SEF) was studied by analyzing presaccadic activity, electrically elicited saccades, and the relationship between them. Response-field optimal vectors, defined as the visual field coordinates or saccadic eye-movement dimensions evoking the highest neural discharge, were quantitatively estimated for 160 SEF neurons by syste...

Characteristics Higher Level Structures SEF is located at the rostral end of the supplementary motor area, contiguous with the representation of orofacial, pinna and forelimb movements. SEF is located in Brodman’s area 6 and corresponds to area F7 [1]. The human SEF is located on the medial surface of the superior frontal gyrus in the upper part of the paracentral sulcus (Fig. 1). 10.1007/978-3...

Cortical motor areas are thought to contribute "higher-order processing," but what that processing might include is unknown. Previous studies of the smooth pursuit-related discharge of supplementary eye field (SEF) neurons have not distinguished activity associated with the preparation for pursuit from discharge related to processing or memory of the target motion signals. Using a memory-based ...

This work aims to improve expressive speech synthesis of ebooks for multiple speakers by using training data from many audiobooks. Audiobooks contain a wide variety of expressive speaking styles which are often impractical to annotate. However, the speaker-expression factorization (SEF) framework, which has been proven to be a powerful tool in speaker and expression modelling usually requires t...

Together with the frontal and parietal eye fields, the supplementary eye field (SEF) is involved in the performance and control of voluntary and reflexive saccades and of ocular pursuit. This region was first described in non-human primates and is rather well localized on the dorsal surface of the medial frontal cortex. In humans the site of the SEF is still ill-defined. Functional imaging tech...

Single-unit recording in monkeys and functional imaging of the human frontal lobe indicate that the supplementary eye field (SEF) and the frontal eye field (FEF) are involved in ocular decision making. To test whether these structures have distinct roles in decision making, single-neuron activity was recorded from each structure while monkeys executed an ocular go/nogo task. The task rule is to...

Receptor tyrosine kinases (RTKs) control a multitude of biological processes and are therefore subjected to multiple levels of regulation. Negative feedback is one of the mechanisms that provide an effective means to control RTK-mediated signaling. Sef has recently been identified as a specific antagonist of fibroblast growth factor (FGF) signaling in zebrafish and subsequently in mouse and hum...