نتایج جستجو برای: sedative drug

تعداد نتایج: 592676  

Journal: :Revista brasileira de psiquiatria 2005
Dalva Poyares Luciano Ribeiro Pinto Stella Tavares Sergio Barros-Vieira

The purpose of this updating manuscript is to briefly describe the profile, clinical use and indication of some of the most used sedative and hypnotic compounds. About 2/3 of all hypnotic prescriptions go to chronic use. Benzodiazepines are among the most prescribed drugs worldwide. Women, elderly, psychiatric and medical disease patients are among chronic users of hypnotics. Zolpidem is now th...

Journal: :Biopharmaceutics & Drug Disposition 2021

Zaleplon (ZP) is a sedative and hypnotic drug used for the treatment of insomnia. Despite its potent anticonvulsant activity, ZP not commonly convulsion since characterized by low oral bioavailability as result poor solubility extensive liver metabolism. The following study aimed to formulate specifically controlled release nano-vehicles parenteral delivery enhance biological activity. A modifi...

Journal: :BMJ open 2015
Helene G van der Meer Hans Wouters Rolf van Hulten Niesko Pras Katja Taxis

INTRODUCTION Older people often use medications with anticholinergic or sedative side effects which increase the risk of falling and worsen cognitive impairment. The Drug Burden Index (DBI) is a measure of the burden of anticholinergic and sedative medications. Medication reviews are typically done by a pharmacist in collaboration with a general practitioner to optimise the medication use and r...

Journal: :Critical Care 2008
Matthias Haenggi Heidi Ypparila-Wolters Christine Bieri Carola Steiner Jukka Takala Ilkka Korhonen Stephan M Jakob

INTRODUCTION Sedative and analgesic drugs are frequently used in critically ill patients. Their overuse may prolong mechanical ventilation and length of stay in the intensive care unit. Guidelines recommend use of sedation protocols that include sedation scores and trials of sedation cessation to minimize drug use. We evaluated processed electroencephalography (response and state entropy and bi...

2001
John P. Kress Anne S. Pohlman

• Objective: To assess the impact of daily interruption of sedative infusions on duration of mechanical ventilation and length of stay (LOS) in patients receiving either midazolam and morphine or propofol and morphine. • Design: Randomized controlled trial. • Setting and participants: 128 mechanically ventilated adult patients receiving continuous sedative infusions in a medical intensive care ...

حاجی محمدی, امیر, حسین پور, رضا, دلارام, اعظم, شایسته, یعقوب, شکرزاده, محمد,

Background and purpose: Intentional drug poisoning is one of the most common methods of suicide attempt. The purpose of this study was to determine the demographic characteristics of suicide attempters and identifying the pattern of intentional drug poisoning. Materials and methods: We conducted a descriptive-analytical study in which data was collected from the medical records of suicide at...

2000

The Classification of Psychoactive Drugs Sedative Hypnotics and Antianxiety Agents Focus on Disorders: Fetal Alcohol Syndrome Antipsychotic Agents Antidepressants Focus on Disorders: Depression Narcotic Analgesics Stimulants Drugs, Experience, Context, and Genes Tolerance Sensitization Addiction and Dependence Explaining Drug Abuse Behavior on Drugs Why Doesn’t Everyone Abuse Drugs? Can Drugs C...

Journal: :Critical care medicine 2007
Craig R Weinert Andrew D Calvin

OBJECTIVE Describe the pharmacoepidemiology of sedative medications and nurse-rated patients' behavior and sedation adequacy. DESIGN Cohort study, 2001-2003. PATIENTS Patients ventilated for >36 hrs in a medical or surgical intensive care unit at a university-affiliated hospital. Proxies for 312 eligible subjects were approached for consent, 277 subjects enrolled, and data from 274 subjects...

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