Brown tumors are expansile osteolytic lesions of bone, occurring in hyperparathyroidism. They occur more commonly in primary hyperparathyroidism, and tend to regress after the removal of parathyroid adenomas [1]. They are much less common in secondary hyperparathyroidism but have been reported [1]. Brown tumors occur most commonly in ribs , mandible, clavicle, and pelvis, and are uncommon in th...

Secondary hyperparathyroidism is an unusual complication of hypophosphatemic rickets during the treatment. As there is growing evidence that a high phosphate diet may induce secondary hyperparathyroidism and even tertiary hyperparathyroidism caused by hyperplasia of the parathyroid glands. Serum calcium, phosphate and also parathyroid hormone should be measured regularly to catch the early diag...

Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated secondary hyperparathyroidism. It is described by severe skeletal deformities, high level of PTH in patients with chronic renal failure, and deformed face. This paper reports a 44-year-old male patient with the mentioned characteristics. In addition to the unique clinical features, high levels of ALP and PTH hormon...

primary or secondary hyperparathyroidism can present with a brown tumor of the mandible. involvement of other skull and facial bones is extremely rare. only a few cases with brown tumor of the orbital bones have been reported. an is year old girl with primary hyperparathyroidism presented with unilateral exophthalmos caused by brown tumor of the orbital roof, lite patient had a 1.5 cm palpable ...

Cinacalcet, a calcimimetic drug, is now used to treat secondary hyperparathyroidism in dialysis patients. The treatment response varied and failure common. This study aimed evaluate factors affecting unsuccessful responses of cinacalcet chronic patients with hyperparathyroidism.

Secondary hyperparathyroidism is a common complication for patients with end-stage renal disease (ESRD). When it progresses, it is associated with morbidity and mortality [1]. Phosphate binders and vitamin D can be used to prevent the progression of secondary hyperparathyroidism. However, these conservative treatments often fail to control severe hyperparathyroidism. In such cases, parathyroide...

Brown tumor represents a serious and late bony complications of advanced hyperparathyroidism with a frequency of 1.5–1.75 percent in secondary hyperparathyroidism and 3–4 percent in primary hyperparathyroidism. [1,2] Here we describe an extremely rare case of a 19-year-old male patient with a brown tumor localised in the maxilla and mandibular due to secondary hyperparathyroidism compromising m...

BACKGROUND Treatment options for secondary hyperparathyroidism were significantly amended with the introduction of cinacalcet and paricalcitol. Limitations of resources in public health systems demand detailed analyses of accruing costs. The aim of this study was to compare the costs of these new treatment modalities to surgery. METHODS Patients who underwent initial parathyroidectomy (n = 91...

Introduction: Hyperparathyroidism is presented with increased parathyroid hormone (PTH) secretion due to hyperfunctioning of one or more of the four parathyroid glands. Primary hyperparathyroidism (p-HPT) can be due to parathyroid adenoma, hyperplasia or carcinoma of the parathyroid gland. Secondary hyperparathyroidism (s-HPT) is usually a response to hypocalcaemia and consecut...

A neonate was found to have normocalcaemic hyperparathyroidism with bone disease. The plasma parathyroid hormone concentration returned to normal by 4 weeks, and healing of the bone lesions was evident by age 5 months. The mother proved to have pseudohypoparathyroidism, previously unsuspected.