730 To the Editor: Pilomatricoma is a benign neoplasm that is generally straightforward to diagnose clinically. It initially takes the form of a small tumor of nonspecific appearance but displays a characteristic firm consistency to palpation as it develops. We present the case of a giant pilomatricoma on the scalp, noting the abnormal morphology and rapid growth. We also describe a surgical so...

sebaceous carcinoma is a relatively rare cutaneous tumor that is most commonly derived from the sebaceous glands located in periorbital area. the extraocular occurrence of this tumor is very rare. we report a case of an 85 years old woman who presented with a slowly enlarging mass on the right temporal region. histological examination of the lesion revealed a malignant sebaceous carcinoma occur...

The title “Metastasis of a Basal-cell Epithelioma” might be considered a “ contradiction in terms,” as absence of metastasis is generally considered one of the cardinal characteristics of basal-cell epithelioma. Sutton (1) defines basal-cell epithelioma as “ a comparatively benign variety of carcinoma of the skin which probably develops from the basal layer of the epidermis or from the skin gla...

Three different types of tumors are known to develop from the pars ciliaris reti­ nae: the benign Fuchs epithelioma, the ma­ lignant medullo-epithelioma of the embry­ onic type, and the malignant medullo-epi­ thelioma of the adult type. Chart 1 indicates the relationship of these tumors to the prim­ itive retinal elements and to the tumors of other parts of the retina. The Fuchs epithelioma sim...

Introduction: This is to report a rare case of sebaceous carcinoma of inner cantus of the eye in relation with rare skin lesions of epidermodysplasia verruciformis. Epidermodysplasia verruciformis is a rare skin disease which is caused by human papilloma virus. Sebaceous carcinoma is a rare entity which is derived from sebaceous glands and to our best knowledge this is for the first time that w...

The predisposition to epithelial neoplasms in nevus sebaceous is well established; most tumors occur in adults and are benign. Hidradenoma is a relatively rare benign tumor of sweat gland origin that can rarely arise within a nevus sebaceous. We present an interesting case of a hidradenoma and sebaceoma arising within a nevus sebaceous and present a literature review of the 2 conditions. Even t...

Extraocular sebaceous carcinoma is a relatively rare skin appendage carcinoma [1]. Although ocular sebaceous carcinoma is thought to arise from the Meibomian glands and glands of Zeis, there is no evidence that extraocular sebaceous carcinoma arises from pre-existing sebaceous glands [2]. Most sebaceous carcinomas are invasive [1], however, only a few cases of sebaceous carcinoma associated wit...

Sebaceous carcinoma is a malign tumor of sebaceous glands and it is usually found on the eyelid. However, sebaceous carcinoma can arise anywhere in the body where sebaceous glands exist. Extraocular localization of the sebaceous carcinoma is rare and accounts for 25% of all cases. Sebaceous carcinoma is more common in women between the ages of 60 and 70. Moreover, Asian population is more likel...

BACKGROUND Sebaceous glands contribute significantly to the barrier functions of the skin. However, little is known about their homeostasis and tumorigenesis. Recently, increased expression of stem cell marker Lrig1 has been reported in sebaceous carcinoma-like tumors of K14ΔNLef1 transgenic mice. In this study, we analyzed the Lrig1 expression in human sebaceous tumors. METHODS Twenty-eight ...