Lentinula edodes (L. edodes), which imparts various health benefits to humans, is considered a novel source of soluble dietary fiber (SDF). In this study, ultrasonic-assisted hot-water method was used extract SDF (U-SDF) from L. edodes, and physicochemical, antioxidant hypoglycemic properties the U-SDF were investigated. Physicochemical showed that water solubility, holding capacity, swelling o...

stromal derived factor-a (sdf-1-a) is a cxc chemokine which has been demonstrated as a recruitment factor for leukocytes to the site of inflammation, infection, injury and following stress. this chemokine has been shown to be expressed by liver cells and in liver diseases. hence, the aim of this study was to examine the expression of sdf-1 by hepatocytes in responses to the stress imposed durin...

background: mesenchymal stem cells (mscs) are recently introduced as novel immunological gene carriers for treatment of cancer. it is believed that balance between the expression of angiogenic and anti-angiogenic factors, such as sdf-1 and ip-10, may regulate neovascularization within the tumor. methods: in this study, we compared the expression of important tumor promoting mediators in ip-10-t...

AIMS We hypothesized that preconditioning (PC) with stromal-derived factor 1 alpha (SDF-1) significantly enhances cell survival, proliferation, and engraftment of bone marrow-derived mesenchymal stem cells (MSCs) via SDF-1/CXCR4 signaling. METHODS AND RESULTS MSCs were cultured and then incubated in medium for 60 min without SDF-1 (control group) or with SDF-1 0.05 microg/mL (SDF-1 group) or ...

nloaded kground: Stromal cell–derived factor-1 (SDF-1) and its receptor, CXCR4, have been shown to mediate veness and metastatic behavior in a number of cancers, including ovarian, prostate, bladder, breast, and atic cancers. The expression and significance of SDF-1 in pancreatic ductal adenocarcinoma (PDA) ot been systematically studied. thods: We examined the expression of SDF-1 by immunohist...

BACKGROUND The CXC chemokine receptor 4 (CXCR4) and its ligand, stromal cell-derived factor-1 (SDF-1alpha or CXC chemokine ligand 12) are involved in the trafficking of leukocytes into and out of extravascular tissues. The purpose of this study was to determine whether SDF-1alpha secreted by host cells plays a role in recruiting inflammatory cells into the periodontia during local inflammation....

Stromal cell-derived factor-1α (SDF-1α) is a well-characterized chemokine that mobilizes stem cells homing to the ischemic heart, which is beneficial for cardiac regeneration. However, clinically administered native SDF-1α diffuses quickly, thus decreasing its local concentration, and results in side effects. Thus, a controlled release system for SDF-1α is required to produce an effective local...

A set A ⊆ N is square-difference free (henceforth SDF) if there do not exist x, y ∈ A, x 6= y, such that |x − y| is a square. Let sdf(n) be the size of the largest SDF subset of {1, . . . , n}. Ruzsa has shown that sdf(n) = Ω(n65 ) = Ω(n0.733077···) We improve on the lower bound by showing sdf(n) = Ω(n205 ) = Ω(n0.7334···) As a corollary we obtain a new lower bound on the quadratic van der Waer...

OBJECTIVE Although stromal cell-derived factor (SDF)-1αis well known to modulate the mobilization of hematopoietic stem cells and endothelial progenitor cells, its effects on some pre-existing vascular functions remain unknown. We have investigated here the role of SDF-1αsignaling in endothelial barrier function. APPROACH AND RESULTS Treatment with SDF-1α elevated transendothelial electrical ...