Article Type Research Article Authors Soufiabadi M.* PhD

The bioactive component harpagoside was successfully separated from the crude extract of Scrophularia ningpoensis Hemsley by one-step purification using high-speed counter-current chromatography (HSCCC). A two-phase solvent system containing n-butanol:ethyl acetate:water (1:9:10) was selected following consideration of the partition coefficient of the target compound. A 276 mg quantity of the c...

Article Type Research Article Authors Soufiabadi M.* PhD

In recent years, marine algae have emerged as a rich and promising source of molecules with potent activities against various human pathogens. The widely distributed brown alga Lobophora variegata that is often associated with tropical coral reefs exerts strong antibacterial and antiprotozoal effects, but so far has not been associated with specific anti-viral activities. This study investigate...

Although habitat loss and fragmentation threaten species throughout the world and are a major threat to biodiversity, it is apparent that some species are at greater risk of extinction in fragmented landscapes than others. Identification of these species and the characteristics that make them sensitive to habitat fragmentation has important implications for conservation management. Here, we pre...

AIM To investigate the antioxidative activity of the constituents of the roots of Scrophularia ningpoensis (Chinese name: Xuanshen). METHODS The main compounds from the roots of Scrophularia ningpoensis were isolated and identified by chromatography and FABMS, NMR etc. Using the techniques of pulse radiolysis, the electron transfers from iridoid glycosides (IG) or phenylpropanoid glycosides (...

Background: Numerous plants in traditional practices of medicine have been used to treat cognitive disorders, including neurodegenerative diseases such as Alzheimer’s disease (AD) and other memory related disorders. Materials and Methods: We present here the evaluation of acetylcholinesterase (AChE) inhibitory and antioxidant activities of the aqueous methanol extracts of five traditional medic...

Traditional plant healing for diabetes has shown a surging significance in the last few decades. Therefore, the purpose of this study was to evaluate the hypoglycemic effect of the aqueous extract of E.variegata bark in diabetic rats. Diabetes was induced in rats by intraperitoneal administration of 45 mg/kg of streptozotocin (STZ). The aqueous extract of E. variegata was administered in the ra...

Differences between taxa which have developed in allopatry can contribute to reproductive isolation in the case of secondary contact. Hybrid zones are ideal study systems in which to investigate the role of preand postzygotic mechanisms for the reduction or inhibition of gene flow. This thesis describes a hybrid zone between the fire-bellied toads Bombina bombina and B. variegata in Romania. Th...

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