BACKGROUND Both Schistosoma mansoni and Schistosoma haematobium cause schistosomiasis in sub-Saharan Africa. We assessed the diagnostic value of selected Schistosoma antigens for the development of a multiplex serological immunoassay for sero-epidemiological surveillance. METHODOLOGY/PRINCIPAL FINDINGS Diagnostic ability of recombinant antigens from S. mansoni and S. haematobium was assessed ...

Myelitis is a rare complication of Schistosoma mansoni, and is characterized by a dramatic involvement of the lower part of the spinal cord [1 , 2]. Early antischistosomal therapy is able to improve markedly clinical signs [3, 4J. Myelography and CT (3, 5-1 OJ are normal in most cases of Schistosoma mansoni transverse myelitis (2, 1 OJ . As far as we know, no MR studies have been reported. We p...

Egyptian subjects living in areas endemic for Schistosoma mansoni or Schistosoma haematobium were selected on the basis of their apparent extremes of resistance or susceptibility to schistosomiasis and examined for T and B cell responses against the major electrophoretically resolved protein species from soluble adult worm extracts. A 42-kDa band was specifically recognized by a significant maj...

Most Schistosoma mansoni experimental infections are developed in several inbred strains of Mus musculus as definitive host. In contrast, Mus spretus is unexplored in Schistosoma infection studies. Mus spretus provides a high variation of immunological phenotypes being an invaluable tool for genetic studies and gene mapping. The aim of this study is to characterize hematological and immunologic...

Background: Schistosoma mansoni infection is associated with hepatic fibrosis and portal hypertension. Previous studies reported that blocking some components of rennin angiotensin system can ameliorate the liver pathology induced by S. mansoni infection. Aim: The present study investigated potential effect losartan, an II receptor antagonist, enalapril, angiotensin-converting enzyme inhibitor,...

OBJECTIVES Recent reports suggest that Schistosoma infection may increase the risk of acquiring human immunodeficiency virus (HIV). We used data from a large cross-sectional study to investigate whether Schistosoma mansoni infection is associated with increased HIV prevalence. METHODS We conducted a household survey of residents in island fishing communities in Mukono district, Uganda, betwee...

Schistosoma mansoni, which causes schistosomiasis has humans as the primary definitive host and mollusks Biomphalaria glabrata, B. straminea tenagophila intermediate hosts. The goal of this research was to undertake a malacological survey on watercourses in city Betim, using data provided by city´sHealth´s Department. were collected from pre-selected sites, examined for presence cercariae taxon...

Male Indian buffalo (Bubalus bubalis) calves were submitted to Schistosoma mansoni infection by percutaneous, oral and subcutaneous routes. No worms or eggs were found in four of the animals tested. Bubalus bubalis appears to be refractory for S. mansoni.

The aim of the present work was to investigate the Schistosoma mansoni and Fasciola gigantica cross-reactivity between adult worms and egg homogenates of the parasites. Immunoprophylactic effects of crude Schistosoma mansoni worms and egg antigens mixed with or without saponins extracted from Atriplex nummularia were studied followed by challenge with 80 cercariae of Schistosoma mansoni. Our re...