OBJECTIVES To derive and validate a clinical score to risk stratify children presenting with acute infection. STUDY DESIGN AND PARTICIPANTS Observational cohort study of children presenting with suspected infection to an emergency department in England. Detailed data were collected prospectively on presenting clinical features, laboratory investigations and outcome. Clinical predictors of ser...

Lysophosphatidic acid (LPA), which is proposed to play an important role in normal physiological situations such as wound healing, vascular tone, vascular integrity and reproduction, may be involved in the etiology of some diseases such as atherosclerosis, cancer, obesity or myocardial infarction. Abnormal findings, including silent brain infarction (SBI), are frequently observed by magnetic re...

With the increasing size of the elderly population and evolving imaging technology, silent brain infarction (SBI) has garnered attention from both the public and the physicians. Over 20% of the elderly exhibit SBI, and the prevalence of SBI increases steadily with age, ie, 30%-40% in those older than 70 years. Well-known cardiovascular risk factors such as hypertension has been identified as a ...

AIMS To determine the acceptability to university students of practitioner-delivered screening and brief intervention (SBI) versus a novel approach-web-based SBI (e-SBI). METHODS A random sample of 1910 university students was invited to indicate their preferences for various brief intervention approaches in an internet survey. RESULTS e-SBI was the most popular intervention. It was favoure...

PURPOSE Previous studies have shown that oral administration of bovine immunoglobulin protein preparations is safe and provides nutritional and intestinal health benefits. The purpose of this study was to evaluate the plasma amino acid response following a single dose of serum-derived bovine immunoglobulin/protein isolate (SBI) and whether bovine immunoglobulin G (IgG) is present in stool or in...

OBJECTIVE To determine whether there exists a population of Dutch women with a high prevalence of antipolymer antibodies (APA) and severe health complaints/symptoms, and exposure to a silicone breast implant (SBI). As the antigen-specific nature of the antipolymer antibody has not yet been established, we refer to the term polymer binding immunoglobulins. METHODS The study population was sele...

INTRODUCTION Indigenous Australians experience a disproportionately high burden of alcohol-related harm. Alcohol screening and brief intervention (SBI) offers the potential to reduce this harm if barriers to its delivery in Aboriginal Community Controlled Health Services (ACCHSs) can be optimally targeted. AIMS . Examine health-care practitioners' perceptions of, and practices in, alcohol SBI...

The second immunoglobulin-binding protein (Sbi) of Staphylococcus aureus has two N-terminal domains that bind the Fc region of IgG in a fashion similar to that of protein A and two domains that can bind to the complement protein C3 and promote its futile consumption in the fluid phase. It has been proposed that Sbi helps bacteria to avoid innate immune defenses. By comparing a mutant defective ...

Objective: To estimate incidence of Reactive Thrombocytosis among febrile infants and assess utility of platelet count as a potential predictor and diagnostic tool of serious bacterial infection .Design:Prospective non randomized study conducted between April 2011 to March 2012Setting: Tertiary care pediatric unit.Inclusion criteria:All infants 30 to 89 days of age, admitted with rectal tempera...

This presentation addressed cultural considerations and sensitivities particularly relevant to the southern US when providing alcohol screening and brief intervention (SBI) to individuals demonstrating risky drinking behavior. Broader implications for education and training were also reviewed. The literature has begun to identify key issues pertaining to cultural sensitivities and consideration...