OBJECTIVE To estimate the potential impact on cardiovascular health of modifying dietary intake of saturated fat across the New Zealand population, and whether this would be appropriate and feasible. METHODS First, a literature review of meta-analyses was conducted to estimate the magnitude of reduction in risk for cardiovascular events in response to a reduction in dietary saturated fat inta...

PURPOSE To compare the detectability of vertebral metastatic disease on T1-weighted, short-inversion-time inversion recovery (STIR), fast spin-echo (FSE), fat-saturated FSE, and inversion recovery FSE (IRFSE) MR sequences using percent contrast and contrast-to-noise ratios. METHODS Patients with proved metastatic disease underwent imaging on a 1.5-T MR system with sagittal T1-weighted (800/20...

OBJECTIVE This article investigates the effects of a brief psychological intervention-implementation intentions training-on the reduction of saturated fat intake among patients after myocardial infarction (MI). METHODS One hundred fourteen patients who had experienced a first uncomplicated MI took part in the study. Data were collected at approximately 1 week after MI, 2 weeks after short-ter...

We examined the effects of dietary cholesterol (less than 0.01 and 1.7 mg/Kcal) and type of fat (saturated, coconut oil; polysaturated, corn oil) on very low density plus low density lipoprotein (VLDL + LDL) and high density lipoprotein (HDL) cholesterol in 24 young baboons (12 male, 12 female) Paplo sp.) in a crossover design experiment. The oils contributed 40% of calories. Total serum choles...

Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong. A landmark systematic review and meta-analysis of observational studies showed no association between saturated fat consumption and (1) all-cause mortality, (2) coronary hear...

BACKGROUND Previous studies have shown that increases in LDL-cholesterol resulting from substitution of dietary saturated fat for carbohydrate or unsaturated fat are due primarily to increases in large cholesterol-enriched LDL, with minimal changes in small, dense LDL particles and apolipoprotein B. However, individuals can differ by their LDL particle distribution, and it is possible that this...

Dietary fat and oxidative stress are hypothesized to contribute to non-alcoholic fatty liver disease and progression to steatohepatitis. To determine the effects of dietary fat content on hepatic triglyceride, body fat distribution and markers of inflammation and oxidative stress, overweight/obese subjects with normal glucose tolerance consumed a control diet (CONT: 35% fat/12% saturated fat/47...