BACKGROUND The purpose of this study was to assess the late side effects of radioiodine therapy (RIT) on salivary gland function. One hundred eighty two patients were evaluated. METHODS Assessment of salivary gland function was performed with salivary gland scintigraphy (SGS), sialometry, and subjective open questions to determine common side effects of RIT on salivary gland function. RESUL...

UNLABELLED Salivary gland dysfunction has been described in patients undergoing radioiodine therapy but associated lacrimal gland dysfunction (sicca syndrome) has never been reported. We conducted a prospective cohort study with follow-up for up to 3 y in a tertiary care university center to determine the prevalence of sicca syndrome in patients after high-dose radioiodine treatment. METHODS ...

background: salivary gland tumors are relatively uncommon and they consist of 3-10% of head and neck neoplasms. most of studies have shown geographic variation in the incidence and histopathologic types of salivary gland neoplasms. the aim of this study was to evaluate the salivary gland tumors in isfahan for 10 years duration. materials and methods: in this epidemiological study, 229 medical r...

BACKGROUND Salivary gland dysfunction with xerostomia is a major clinical problem without a causal therapy in most cases. The development of an animal model for scintigraphic assessment of salivary gland function has great clinical relevance for the investigation of promising new diagnostic and therapeutic strategies for chronic salivary gland diseases. This study reports the first experiences ...

this evidence-based article reviews risk indicators and management of unknown-origin xerostomia. xerostomia and hyposalivation refer to different aspects of dry mouth. xerostomia is a subjective sensation of dry mouth, whilst hyposalivation is defined as an objective assessment of reduced salivary flow rate. about 30% of the elderly (65 years and older) experience xerostomia and hyposalivation....

The standard of care for head and neck cancer typically includes surgical resection of the tumor followed by targeted head and neck radiation. However depending on tumor location and stage, some cases may not require surgical resection while others may be treated with chemoradiation. Unfortunately, these radiation treatments cause chronic negative side effects for patients. These side effects a...

BACKGROUND Early studies suggested that salivary gland dysfunction was a normal sequela of aging. Recent research on healthy, different-aged adults has led to a revision of these former conclusions. Parotid gland function appears to be age-stable, yet there is no consensus on submandibular/sublingual output. To date, there have only been two longitudinal studies utilizing healthy individuals ex...

Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is treated by substitution with artificial saliva, rather than through functional restoration of the glands. During embryogenesis, the ectodysplasin/...

Sialolithiasis is a common disease of the salivary glands and a major cause of salivary gland dysfunction. It commonly affects middle-aged and has male predominance. Submandibular gland or its duct is most commonly affected. The size of salivary calculi may vary from less than 1 mm to a few cm in the largest diameter. Salivary stones that exceed 15 mm in any dimension are classified as giant. A...