Saliva is secreted into the mouth at a rate of 0.3 to 0.4 ml per minute. Retained saliva in the mouth physiologically triggers swallowing to carry the saliva out of the mouth. Dawes (1983) have reported the volume of saliva in the mouth just before swallowing, the rate of swallowing, the volume swallowed per swallow, and the volume of saliva in the mouth just after swallowing. Clearance of mate...

When a constant dose of digoxin was administered orally over several days, the digoxin concentration in saliva and erythrocytes rose faster than in serum. Thus, the saliva/serum concentration ratio was below 1.0 after a single dose and above 1.0 in the steady state. The digoxin concentration was relatively high in "unstimulated" (more or less spontaneous) saliva and decreased with stimulation o...

Decreases in saliva secretion compromise food mastication and swallowing, reduce mucosal immune function, and increase the risk for oral diseases like dental caries. Chlorella is a green alga that contains a variety of nutrients including amino acids, vitamins, and minerals. In our previous study, Chlorella-derived multicomponent supplementation did not affect salivary flow rates in healthy you...

background: saliva is an alternative biological matrix in drug testing. it has several advantages in comparison with other biological fluids such as blood and urine. collection of saliva is simple, noninvasive and can be controlled under direct observation in drug abusers, or opium addicts.   methods: in the present study we report our experience with saliva collection, liquid-liquid extraction...

The presence of hyaluronan (HA), hyaluronidase and hyaluronidase inhibitors has been assayed in pure resting and stimulated parotid saliva and also in resting and stimulated mixed saliva utilizing an ELISA-type assay and its modifications. Results confirmed the presence of hyaluronan in all saliva specimens which generally decreased upon stimulation. Hyaluronan in parotid saliva was of high mol...

BACKGROUND Leishmania transmission occurs in the presence of insect saliva. Immunity to Phlebotomus papatasi or Lutzomyia longipalpis saliva or salivary components confers protection against an infection by Leishmania in the presence of the homologous saliva. However, immunization with Lutzomyia intermedia saliva did not protect mice against Leishmania braziliensis plus Lu. intermedia saliva. I...

Objectives: Diabetes mellitus is one of the most common chronic diseases that may cause irreversible complications. This disease can affect the salivary glands and oral health. Among physical and chemical alterations, changes in the pH and viscosity of saliva are particularly important. The aim of this study was to compare the pH and viscosity of unstimulated saliva in diabetic patients and non...

cigarette smoke is injurious to both oral cavity and internal body environment. saliva is the firstbody fluid to encounter the dangerous smoke. the aim of our present study was, therefore, toevaluate the influence of smoking on the antioxidant activity of saliva of healthy smokers.antioxidant capacity of saliva was determined using different methods in the centrifuged saliva from25 male smokers...