نتایج جستجو برای: saf mannan

تعداد نتایج: 3481  

2017
Muhammad Saeed Ahmad Torben Kimhofer Sultan Ahmad Mohammed Nabil AlAma Hala Hisham Mosli Salwa Ibrahim Hindawi Dennis O. Mook-Kanamori Katarína Šebeková Zoheir Abdullah Damanhouri Elaine Holmes

Skin auto fluorescence (SAF) is used as a proxy for the accumulation of advanced glycation end products (AGEs) and has been proposed to stratify patients into cardiovascular disease (CVD) and diabetes mellitus (DM) risk groups. This study evaluates the effects of seven different ethnicities (Arab, Central-East African, Eastern Mediterranean, European, North African, South Asian and Southeast As...

2016
Robert P. van Waateringe Sandra N. Slagter Melanie M. van der Klauw Jana V. van Vliet‐Ostaptchouk Reindert Graaff Andrew D. Paterson Helen L. Lutgers Bruce H. R. Wolffenbuttel

BACKGROUND Skin autofluorescence (SAF) is a noninvasive marker of advanced glycation end products (AGEs). In diabetes, higher SAF levels have been positively associated with long-term complications, cardiovascular morbidity and mortality. Because little is known about the factors that influence SAF in nondiabetic individuals, we assessed the association of clinical and lifestyle parameters with...

2012
Pascal Barat Benoît Cammas Aurélie Lacoste Jérôme Harambat Vanessa Vautier Fabienne Nacka Jean-Benoît Corcuff

A dvanced glycation end product (AGE) burden can be indirectly quantified in vivo by measuring skin autofluorescence (SAF) (1). It has been recently published by Felipe et al. (2) that SAF is correlated with glycated he-moglobin (GHb) but not with mean blood glucose (MBG) in type 1 diabetic children. This suggests that factors besides MBG exposure may be influential in skin AGE generation. In t...

Objectives: The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. Materials and Methods: SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...

2013
Andries J. Smit Jitske M. Smit Gijs J. Botterblom Douwe J. Mulder

AIM Diabetes (DM) and impaired glucose tolerance (IGT) detection are conventionally based on glycemic criteria. Skin autofluorescence (SAF) is a noninvasive proxy of tissue accumulation of advanced glycation endproducts (AGE) which are considered to be a carrier of glycometabolic memory. We compared SAF and a SAF-based decision tree (SAF-DM) with fasting plasma glucose (FPG) and HbA1c, and addi...

Journal: :Journal of immunology 2006
Alpana Ray Arvind Shakya Deepak Kumar Merrill D Benson Bimal K Ray

Abundantly expressed serum amyloid A (SAA) protein under chronic inflammatory conditions gives rise to insoluble aggregates of SAA derivatives in multiple organs resulting in reactive amyloid A (AA) amyloidosis, a consequence of rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, familial Mediterranean fever, and Castleman's disease. An inflammation-responsive transcription factor, S...

2015
THEODORE W. LETCHER JUSTIN R. MINDER

Midlatitude mountain regions are particularly sensitive to climate change because of an active snow albedo feedback (SAF). Here, the SAF is characterized and quantified over the complex terrain of the Colorado Headwaters region using high-resolution regional climate model simulations. A pair of 7-yr control and pseudo-global warming simulations is used to study the regional climate response to ...

2015
Muhammad S. Ahmad Zoheir A. Damanhouri Torben Kimhofer Hala H. Mosli Elaine Holmes

Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases. Non-invasive skin autofluorescence (SAF) measurement serves as a proxy for tissue accumulation of AGEs. We assessed reference SAF and skin reflectance (SR) values in a Saudi population (n = 1,999) and evaluated the existing...

2016
Josine C. van der Heyden Erwin Birnie Dick Mul Sarah Bovenberg Henk J. Veeze Henk-Jan Aanstoot

BACKGROUND Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate the applicability of assessing skin advanced glycation end products (sAGEs) by skin autofluorescence (SAF) as a potential surrogate risk marker. METHODS This study included a cr...

2015
Alpana Ray Bimal K Ray

In the majority of breast cancers, overexpression and hyperactivation of Ras in the tumor microenvironment play significant role in promoting cancer cell growth, angiogenesis, and metastasis. We have previously shown that vascular endothelial growth factor (VEGF) expression in triple negative breast cancer cells is regulated, at least in part, by SAF-1 (serum amyloid A activating factor 1) tran...

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