A sesquiterpene lactone 1-β,10-Epoxy-6-hydroxy-1,10H-inunolide (K100) was isolated through "bioassay-guided fractionation" from Cota palaestina subsp. syriaca, an Eastern Mediterranean endemic plant. K100 inhibited endotoxin- (ET-) induced proinflammatory markers: IL-6, MMP-9, and NO in normal mouse mammary SCp2 Cells. Molecular docking in silico suggested that K100, having highly analogous str...

Vicia palaestina Boiss. is an annual herb that grows in dry areas of eastern Mediterranean countries. It belongs to section Cracca subgenus Vicilla, which characterized by having a high content the non-protein amino acid canavanine. The seeds from some these vetches are also rich lectins. purification and characterization single-chain lectin V. described here. This was most abundant protein alb...

We have characterized three CoA-independent types of enzyme, phospholipases, phospholipid:diacylglycerol acyltransferases (PDATs) and cholinephosphotransferases, responsible for the removal of unusual fatty acids from phosphatidylcholine (PC) in microsomal preparations from developing oil seeds. The metabolism of sn-2-[(14)C]acyl-PC was monitored in microsomal preparations from various oilseeds...

Adaçayı (Salvia spp.) türleri, farmakolojik etkileri güçlü terpenler ve fenolikler başta olmak üzere pek çok sekonder metabolit içermelerinden dolayı tıbbi aromatik değerleri oldukça yüksektir. Bu çalışmada Kahramanmaraş ili florasında doğal olarak yayılış gösteren endemik Salvia pilifera Montbret & Aucher ex Benth., tomentosa Mill., palaestina türlerinin herba kısımlarının uçucu sabit ...

The neuroprotective effect of flower and fruit parts Capparis ovataDesf. var. palaestinaZoh. plant was investigated in H2O2-induced cytotoxicity SH-SY5Y cells. cells were treated with H2O2alone or pretreated (COMFL) extract (COMFR) C. ovatavar. palaestina. MTT, xCELLigence, qualitative quantitative determination phytochemical constituents the extracts by LC-MS/MS methods employed. COMFL COMFR h...