Historically Ruta graveolens L. has been used in many countries, including Brazil, as an abortifacient. Scientists wanted to determine its effect on pregnancy. The active ingredient in Ruta graveolens was given to mice between the first and third day of pregnancy (DOP), between the fourth and sixth DOP or between the seventh and ninth DOP. The extract did not cause preimplantation embryonic los...

Ruta graveolens, Suspension Cultures, Cell-Free System, Acridone Biosynthesis, 1,3-DihydroxyN-methylacridone A cell-free extract of Ruta graveolens cell suspension cultures, strain R-20, was prepared which synthesizes 1,3-dihydroxy-N-methylacridone from N-methylanthranilic acid and malonylcoenzyme A. The reaction is strongly dependent on the presence of ATP. After adding of coenzyme A to the as...

BACKGROUND Recent studies support the use of alpha-agonists during regional anaesthesia in uncomplicated term pregnancies. We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome. METHODS At 117-132 days gestation, chronically instrumented, anaesthetized and mechanically ventilated ewes were rand...

V. L. Pool, C. Jolley, T. Douglas, E. A. Arenholz, and Y. U. Idzerda Department of Physics, Montana State University, Bozeman, Montana 59717, USA Center for Bio-inspired Nanomaterials, Montana State University, Bozeman, Montana 59717, USA Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, USA Astrobiology Biogeocatalysis Research Center, Montana State Un...

GİRİŞ ve AMAÇ: Bu çalışmanın amacı, insan hayvanlar açısından önemli bazı patojenik bakteri mantarlara karşı, hidrodistillasyon yöntemi ile elde edilen GC-MS aile ayrıştırılan 18 çeşit uçucu yağın minimum inhibitör konsantrasyon değerlerini araştırmaktır. YÖNTEM GEREÇLER: Achillea gypsicola (Asteraceae), Ruta graveolens L. (Rutaceae), Satureja hortensis (Lamiaceae), Thymbra spicata biebersteini...

BACKGROUND Since the time when drugs began to be used, it became evident that they could produce a therapeutic effect, but also a clinical condition of toxicity or no effect at all on humans, despite using the same doses in different patients. Such untoward effects were termed "drug idiosyncrasy" and also "idiosyncratic drug effects", but the factors producing such diverse responses were never ...

Homeopathy is considered as one modality for cancer therapy. However, there are only very few clinical reports on the activity of the drugs, as well as in experimental animals. Presently we have evaluated the inhibitory effects of potentized homeopathic preparations against N'-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in rats as well as 3-methylcholanthrene-induced sarcomas in...

The volatile components of the aerial parts of Ruta graveolens and Haplophyllum suaveolens, as well as of leaves of Zanthoxylum limoncello, Z. panamense and Z. setulosum have been studied by GC/MS analysis.

Montana Cooperative Wildlife Research Unit, University of Montana, Natural Sciences 312, Missoula, MT 59812, USA (CRH) U.S. Geological Survey, Montana Cooperative Wildlife Research Unit, University of Montana, Natural Sciences 312, Missoula, MT 59812, USA (MSM) Washington Department of Fish and Wildlife, 2315 North Discovery Place, Spokane Valley, WA 99216, USA (WLM) Wildlife Biology Program, U...