In this issue of the Journal, Mitchell et al. (1) report that lipid-lowering therapy (LLT) was associated with a 36% relative risk reduction (RRR) in all-cause mortality in patients with ischemic heart disease (IHD) enrolled in the Antiarrhythmics Versus Implantable Defibrillator (AVID) trial. This rivals the benefit observed for implantable cardioverter defibrillators (ICDs) over amiodarone th...

A regional regression model was developed to estimate the spatial distribution of ground water recharge in subhumid regions. The regional regression recharge (RRR) model was based on a regression of basin-wide estimates of recharge from surface water drainage basins, precipitation, growing degree days (GDD), and average basin specific yield (SY). Decadal average recharge, precipitation, and GDD...

OBJECTIVE To describe the prevalence of Vitamin D deficiency (VDD) and insufficiency (VDI), and the main dietary sources of vitamin D (VD) in a probabilistic sample of Mexican women at reproductive age participating in Ensanut 2012, stratified by sociodemographic factors and body mass index (BMI) categories. MATERIALS AND METHODS Serum concentrations of 25-hydroxyvitamin-D(25-OH-D) were deter...

INTRODUCTION A disproportionate number of individuals with human immunodeficiency virus (HIV) have mental health and substance-use disorders (MHSUDs), and MHSUDs are significantly associated with their emergency department (ED) visits. With an increasing share of older adults among HIV patients, this study investigated the associations of MHSUDs with ED outcomes of HIV patients in four age grou...

Abstract Introduction Adverse childhood experiences can increase likelihood of hyperarousal, especially around periods vulnerability. Survivors trauma also experience more nightmares. These data explore whether adverse events are associated with adult insomnia severity and Methods Data were obtained from the Sleep Healthy Activity, Diet, Environment, Socialization (SHADES) study N=1007 adults 2...

Selecting the best items in a dataset is a common task in data exploration. However, the concept of “best” lies in the eyes of the beholder: different users may consider different attributes more important, and hence arrive at different rankings. Nevertheless, one can remove “dominated” items and create a “representative” subset of the data set, comprising the “best items” in it. A Pareto-optim...

BACKGROUND Reduced rank regression (RRR) combines exploratory analysis with a-priori knowledge by including risk factors in the model. Dietary patterns, derived from RRR analysis, can be interpreted by the chosen risk factor profile and give an indication of positive or adverse health effects for a specific disease. Our aim was to assess the stability of dietary patterns derived by RRR over tim...

BACKGROUND Individuals with pre-diabetes and diabetes have increased risks of developing macro-vascular complications including heart disease and stroke; which are the leading causes of death globally. The objective of this study was to estimate the prevalence of pre-diabetes and diabetes, and to investigate their predictors among adults ≥18 years in Florida. METHODS Data covering the time pe...

To study the mechanisms of discrimination between various forms of vitamin E, four normal subjects, one patient with lipoprotein lipase deficiency, and three patients with abnormal apolipoprotein B-100 production were given an oral dose containing three tocopherols labeled with differing amounts of deuterium (2R,4'R,8'R-alpha-(5,7-(C2H3)2)tocopheryl acetate (d6-RRR-alpha-tocopheryl acetate), 2S...

BACKGROUND Childhood food allergy and asthma rates are increasing. The hygiene hypothesis has been proposed as an explanation for the increased incidence of allergic disease. OBJECTIVE To describe the association of childhood food allergy and asthma with hygiene factors, such as the number of siblings, antibiotic use, infection history, pet exposure, child care exposure, and maternalchild fac...