Microbiota are found in highly organized and complex entities, known as biofilms, the characteristics of which are fundamentally different from microbes in planktonic suspensions. Root canal infections are biofilm mediated. The complexity and variability of the root canal system, together with the multi-species nature of biofilms, make disinfection of this system extremely challenging. Microbia...

An important consideration in endodontic treatment is the elimination of microorganisms, including fungi, from the complex threedimensional root canal system. Yeasts can be detected in 7-17% of infected root canals. Candida albicans (CA) has a major role in endodontic treatment failure as the most important fungus isolated from the root canal system. C. albicans has been associated with root ca...

INTRODUCTION Microorganisms should be considered to have the major role in starting and perpetuation of pulpo-periapical diseases. Using intracanal medicaments is necessary to gain a bacteria-free environment in the canal system. Calcium hydroxide (abbreviated as Ca(OH)2), which is the most commonly used medicament in endodontic therapy, has been shown to be effective against primary sources of...

IntroductionThe aim of this study is to report the management of large periapical lesion using triple antibiotic paste as an alternative intra-canal medicament in nonsurgical endodontic treatment. Case reportan 11 year old male patient with large periapical lesion in mandibular anterior region, treated using conservative non-surgical endodontic treatment. Calcium hydroxide-iodoform paste (Vitap...

INTRODUCTION Coronal leakage is one of the constant concerns in routine dental practice. It is one of the factors responsible for the failure of root canal therapy. Permanent restorations should be given as soon as possible after the completion of root canal therapy. If unavoidable, provisional restoration should be given in such a way that it maximally reduced the leakage of microorganisms and...

We experienced two cases of inferior alveolar nerve paresthesia caused by root canal medicaments, which were successfully relieved by microscopic endodontic treatment. In the first case, the paresthesia might have been attributable to infiltration of calcium hydroxide into the mandibular canal through the root canals of the mandibular left second molar tooth. In the second case, the paresthesia...

Contemporary endodontics and the future of endodontics are based on regenerative strategies. Success of these regenerative endodontic treatments depends on disinfection of the root canal system. Current research in endodontics focuses on identifying the optimal methods of disinfection of root canal systems to achieve predictable results in revascularization therapy. Although the use of sodium h...

introduction: the purpose of this in vitro study was to compare the ability of triple antibiotic paste (tap) to calcium hydroxide (ch) in disinfecting dentinal tubules. material and methods: sixty root blocks were obtained from extracted single-rooted human teeth. the root canals were enlarged with gates-glidden drills up to size 3 and were contaminated with enterococcus. faecalis ( e. faecalis...

BACKGROUND Bacteria have long been recognized as the primary etiology for pulpal and periapical lesions, which necessitates the elimination of bacteria from the root canal system. In primary teeth, irrigation and debridement is the main protocol required to disinfect the canal. Biomechanical preparation cannot be vigorously done on the primary teeth due to anatomical barrier such as thin and fl...

Microorganisms play a major role in initiation and perpetuation of pulpal and periapical diseases. Therefore, elimination of the microorganisms present in the root canal system is the fundamental objective of endodontic treatment. The use of mechanical debridement, chemical irrigation or other antimicrobial protocols and intra-canal medicaments are critical to attain this goal. The aim of this ...