quantitative relationships between molecular structure of forty eight aldehyde compounds with their known cathepsin k inhibitory effects were discovered by partial least squares (pls) method. evaluation of a test set of 10 compounds with the developed pls model revealed that this model is reliable with a good predictability. since the qsar study was performed on the basis of theoretical descrip...

Criteria based on disturbance rejection and system robustness are proposed to assess the performance of PID controllers. The robustness is measured by a two-block structured singular value, and the disturbance rejection is measured by the minimum singular value of the integral gain matrix. Examples show that the criteria can be applied to a variety of processes, whether they are stable, integra...

In this note we described the robustness properties of optimal risksensitive controllers for quantum systems. We consider a quantum generalization of risk-sensitive criteria using the framework of (James, 2004). The robustness properties are derived by evaluating certain Radon-Nikodym derivatives of the quantum models and of the cost criteria. In addition to induced perturbations in the quantum...

Criteria based on disturbance rejection and system robustness are proposed to assess the performance of PID controllers. A simple robustness measure is defined and the integral gains of the PID controllers are shown to be a good measure for disturbance rejection. An analysis of some well-known PID tuning formulas reveals that the robustness measure should lie between 3 and 5 to have a good comp...

While optimal designs are commonly used in the design of experiments, the optimality of those designs frequently depends on the form of an assumed model. Several useful criteria have been proposed to reduce such dependence, and efficient designs have been then constructed based on the criteria, often algorithmically. In the model robust design paradigm, a space of possible models is specified a...

a common problem arising in project management is the fact that the baseline schedule is often disrupted during the project execution because of uncertain parameters. as a result, project managers are often unable to meet the deadline time of the milestones. robust project scheduling is an effective approach in case of uncertainty. upon adopting this approach, schedules are protected against po...

an optimal desirability function method is proposed to optimize multiple responses in multiple production scenarios, simultaneously. in dynamic environments, changes in production requirements in each condition create different production scenarios. therefore, in multiple production scenarios like producing in several production lines with different technologies in a factory, various fitted res...