نتایج جستجو برای: road eng

تعداد نتایج: 78153  

Journal: :Stroke 2003
Junichiro Satomi Richard J Mount Mourad Toporsian Andrew D Paterson M Christopher Wallace Robert V Harrison Michelle Letarte

BACKGROUND AND PURPOSE Hereditary hemorrhagic telangiectasia type 1 (HHT1) is an autosomal dominant vascular dysplasia caused by mutations in the endoglin gene and characterized by dilated vessels and arteriovenous malformations (AVMs). To understand the etiology of this disorder, we evaluated the cerebral vasculature of endoglin heterozygous (Eng+/-) mice, which represent the only animal model...

2015
Rabab Nasrallah Kathy Knezevic Thuan Thai Shane R. Thomas Berthold Göttgens Georges Lacaud Valerie Kouskoff John E. Pimanda

During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of FLK1(+) mesodermal cells. Endoglin (ENG) is an accessory TGF-β receptor that is enriched on the surface of endothelial and hematopoietic stem cells...

2015
José M. Abril

The reliability of the narrative of the Biblical Exodus has been subject of heated debate for decades. Recent archaeological studies seem to provide new insight of the exodus path, and although with a still controversial chronology, the effects of the Minoan Santorini eruption have been proposed as a likely explanation of the biblical plagues. Particularly, it has been suggested that flooding b...

2017
Calinda K E Dingenouts Wineke Bakker Kirsten Lodder Karien C Wiesmeijer Asja T Moerkamp Janita A Maring Helen M Arthur Anke M Smits Marie-José Goumans

AIMS Hereditary Hemorrhagic Telangiectasia type-1 (HHT1) is a genetic vascular disorder caused by haploinsufficiency of the TGFβ co-receptor endoglin. Dysfunctional homing of HHT1 mononuclear cells (MNCs) towards the infarcted myocardium hampers cardiac recovery. HHT1-MNCs have elevated expression of dipeptidyl peptidase-4 (DPP4/CD26), which inhibits recruitment of CXCR4-expressing MNCs by inac...

2015
Rabab Nasrallah Kathy Knezevic Thuan Thai Shane R. Thomas Berthold Göttgens John E. Pimanda

During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of FLK1 mesodermal cells. Endoglin (ENG) is an accessory TGF-β receptor that is enriched on the surface of endothelial and hematopoietic stem cells an...

2016
June Baik Alessandro Magli Naoyuki Tahara Scott A. Swanson Naoko Koyano-Nakagawa Luciene Borges Ron Stewart Daniel J. Garry Yasuhiko Kawakami James A. Thomson Rita C. R. Perlingeiro

Mechanisms of haematopoietic and cardiac patterning remain poorly understood. Here we show that the BMP and Wnt signalling pathways are integrated in an endoglin (Eng)-dependent manner in cardiac and haematopoietic lineage specification. Eng is expressed in early mesoderm and marks both haematopoietic and cardiac progenitors. In the absence of Eng, yolk sacs inappropriately express the cardiac ...

2015
Rabab Nasrallah Kathy Knezevic Thuan Thai Shane R. Thomas Berthold Göttgens John E. Pimanda

During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of FLK1 mesodermal cells. Endoglin (ENG) is an accessory TGF-β receptor that is enriched on the surface of endothelial and hematopoietic stem cells an...

2000
Göran AP Eriksson Birgitta Olin Krister Svanbro Dalibor Turina

Today, the accumulated volume of data traffic is on the verge of surpassing the accumulated volume of voice traffic in all public networks. Given the growth in the areas of wireless voice and data, we see that the combination of mobile and Internet communication constitutes the driving force behind third-generation wireless systems, which promise to support at least 144 kbit/s (384 kbit/s) in a...

2016

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