background facial wrinkles develop over the natural aging process. the demand to treat these wrinkles is increasing. several treatment options are available. objectives we aimed to investigate the effect of fat injection and its combination with platelet-rich plasma (prp) on facial wrinkles. patients and methods we recruited 28 patients who were candidates for the treatment of facial wrinkles i...

introduction: vesicovaginal fistula remains a challenge in surgical therapy. in this study autologous platelet rich plasma and platelet rich fibrin glue were used as a minimally invasive approach for vesicovaginal fistula closure. materials and methods: data including age, parity, iciq-ui (international consultation on incontinence questionnaire-urinary incontinence), iciq-qol (international co...

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background the platelet-rich plasma (prp) and hyaluronic acid (ha) constitute a system of tissue growth that can regenerate damaged tissue. this study was performed to evaluate the effect of prp and ha in treatment of complications of achilles tendon reconstruction. methods we selected ten patients affected by achilles tendon injuries resulting from post-surgical complications subsequent to ten...

background clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. the aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (prp) injection in healing achilles tendons of rats. methods forty rats were randomly divided into 5 equal groups. sevent...

background:the utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (ppp). this effect is largely mediated by the increased or decreased concentration of platelets in the plasma. the current study aimed to analyze and evaluate the impact of platelet-rich (...

Background: The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect.Methods: We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen matu...

Introduction: Vesicovaginal fistula remains a challenge in surgical therapy. In this study autologous platelet rich plasma and platelet rich fibrin glue were used as a minimally invasive approach for vesicovaginal fistula closure. Materials and Methods: Data including age, parity, ICIQ-UI (International Consultation on Incontinence Questionnaire-urinary incontinence), ICIQ-QOL (Internation...