Acute rheumatic fever is an inflammatory response to group A streptococcal infectionwhich typically occurs two to three weeks after a throat infection.Worldwide, approximately 500 000 new cases of acute rheumatic fever occur annually, and at least 15 million people have chronic rheumatic heart disease. 2 Acute rheumatic fever is characterised by a clinical syndrome, and the most common manifest...

INTRODUCTION Rheumatic heart disease (RHD) is still a common cause of morbidity and mortality in India. Rheumatic fever commonly occurs between 5-15 yrs of age. Rheumatic activity is a common cause of deterioration of symptoms in a stable or undiagnosed case of RHD. MATERIAL AND METHODS 41 consecutive patients of acute rheumatic activity were studied. Presenting symptoms were noted. Physical ...

In the guinea pig, chronic scurvy with superimposed infection (beta streptococcus) and to a lesser extent chronic scurvy alone, produces an arthropathy with striking pathologic similarities to that of rheumatic fever and the closely allied condition of rheumatoid arthritis. Considerable significance is attached to the widespread occurrence in the experimental animal subjected to scurvy and infe...

Introduction Rheumatic fever is a sequel of an immunological disorder initiated by group A beta haemolytic streptococcus (1). It continues to be a major problem in Pediatric population and is one of the leading causes of heart disease in children in the developing countries. The commonest age group involved is 5-15 years (2). Genetic predisposition and overcrowding associated with low socio-eco...

2. Markowitz, M.: Eradication of rheumatic fever. An unfulfilled hope. Circulation, 41:1077, 1970. 3. Czoniczer, C., Lees, M., and Massell, B. F: Streptococcal infection. The need for improved recognition and treatment for the prevention of rheumatic fever. New Eng. J. Med., 265:951, 1961. 4. Grossman, B. J., and Stamler, J.: Potential preventability of first attacks of acute rheumatic fever in...

The levels of streptococcal antibody titers in populations with or without rheumatic fever from an area with a relatively high incidence of rheumatic fever and an area with a low incidence of this disease were compared. Streptococcal antibody titers were determined for two populations, each of which included children without rheumatic fever (nonrheumatic children) and rheumatic fever patients. ...

STUDY OBJECTIVE The aim was to determine the prevalence of rheumatic fever and rheumatic heart disease and to initiate a programme of secondary prophylaxis in Sahafa Town, Sudan. DESIGN The study was a prospective case finding survey, carried out by a specially trained team headed by a cardiologist. SETTING The study involved high risk school children (5-15 years of age) from Sahafa Town in...

Macrophage activation syndrome (MAS) is a rare feature of rheumatic disorders in children and adolescence and its presentation as the first symptom of rheumatic disorders is very infrequent. A 9-year-old girl, in whom MAS developed, was admitted to our Hospital in Tehran, Iran. She suffered from high grade fever and rash followed by multiple joint swelling months afterwards. Bone marrow aspira...

EPISODES of acute rheumatic fever are believed to be triggered by infections with group-A /3-hemolytic streptococei, 10 to 35 days prior to the rheumatic complication. However, both rheumatic fever and rheumatic heart disease are infrequent in Miami, Florida.1' 2 If the incidence rate of rheumatic disease depends on the frequeney of group A streptococei, the low rheumatic rate in Miamni should ...

The diagnosis of acute rheumatic fever is a clinical challenge and depends on the possibility of the disease being borne in mind. Although the complete eradication of rheumatic fever from the Western world has not been achieved, the disease is often forgotten in the differential diagnosis of a patient with fever and polyarthralgia or arthritis. Rheumatic fever remains an important acquired card...