Recent studies conducted in Brazil(1-3) have stressed the importance of the reversed halo sign (RHS) in the diagnosis of lung diseases in immunocompetent patients. However, the RHS in immunocompromised patients has not received the same emphasis. Here, we report the case of a 51-year-old female patient who presented with a 10-day history of generalized ecchymosis and weakness. A complete blood ...

To cite: Nattusamy L, Madan K, Bhalla AS, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-202981 DESCRIPTION A 35-year-old male patient presented with history of fever and cough of 2 months duration. The patient had lost appetite and 8 kg weight over 2 months. On examination of the respiratory system, scattered crackles were audible bilaterally. Rest ...

To cite: Davidsen JR, Madsen HD, Laursen CB. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-213779 DESCRIPTION A 60-year-old woman on no medication, with no obvious exposures and no extrapulmonary symptoms, was referred to diagnostic evaluation due to recurrent pneumonia-like episodes for 6 months. Broad biochemistry, autoimmunology and a body plethysmograp...

1. Professor, Graduate Program in Health Sciences, Faculdade de Medicina de São José do Rio Preto – FAMERP, São José do Rio Preto School of Medicine – São José do Rio Preto, Brazil 2. Adjunct Professor, Faculdade de Medicina de São José do Rio Preto – FAMERP, São José do Rio Preto School of Medicine – São José do Rio Preto, Brazil 3. Physician, Ultra X, São José do Rio Preto, Brazil 4. Professo...

REFERENCES 1. National Clinical Guideline Centre. Chronic obstructive pulmonary disease: management of adults with chronic obstructive pulmonary disease in primary and secondary care. Updated. London: National Clinical Guideline Centre, 2010. 2. Department of Health/Respiratory Team. Consultation on a strategy for services for chronic obstructive pulmonary disease (COPD) in England. London, Dep...

The "reversed halo" sign (RHS) is a distinct radiological sign representing a focal rounded area of ground-glass opacity surrounded by a more or less complete ring of consolidation. Initially, it was reported in two cases of cryptogenic organizing pneumonia and was considered to be relatively specific of the disease. Since then, it has been reported in a wide variety of clinical entities, thus ...

We describe a reversed halo sign in a teenage girl with tuberous sclerosis complex (TSC). Lung manifestations of TSC include lung cysts corresponding to lymphangioleiomyomatosis and small nodules indicating multifocal micronodular pneumocyte hyperplasia (MMPH). However, a reversed halo sign in TSC has never been reported. The lesion was microscopically consistent with MMPH. Immunohistological f...

A reversed halo sign (RHS) is defined as the presence of a focal ring-shaped area of ground-glass opacity within a peripheral rim of consolidation. Although originally described in patients with cryptogenic organizing pneumonia, it has been described with several other noninfectious and infectious diseases, including fungal infections. Thus, it is imperative that a proper diagnosis be establish...