The head direction (HD) system is composed of cells that represent the direction in which the animal's head is facing. Each HD cell responds optimally when the head is pointing in a particular, or preferred, direction. Although vestibular system input is necessary to generate the directional signal, motor/proprioceptive inputs can also influence HD cell responses. Previous studies comparing act...

background: the use of physical restraint as an intervention in the care of psychiatric patients dates back to the beginning of psychiatry. although it is a challenging question, it is still one of the common procedures in psychiatry. considering that very little research has been done in iran in relation to physical restraint, this qualitative study aimed to investigate the experiences of nurs...

There are large disparities in American Indian pediatric motor vehicle (MV) mortality with reports that several factors may contribute. The Fatality Analysis Reporting System for 2000-2014 was used to examine restraint use for occupants aged 0-19 years involved in fatal MV crashes on Indian lands (n = 1667) and non-Indian lands in adjacent states (n = 126,080). SAS GLIMMIX logistic regression w...

Central nociceptin/orphanin FQ (N/OFQ)-expressing neurones are abundantly expressed in the hypothalamus and limbic system and are implicated in the regulation of activity of the hypothalamic-pituitary-adrenal axis (HPA) and stress responses. We investigated the role of the endogenous N/OFQ receptor (NOP) system using the nonpeptidic NOP antagonist, JTC-801 [N-(4-amino-2-methylquinolin-6-yl)-2-(...

The pattern of locomotion following a partial movement restraint was studied in five mongrel puppies. The locomotion of the animals was characterized by enforced pacing during the restraint period and exhibited significant, time dependent gait alterations after removal of the restraint. These changes involved gradual recovery to normal trotting. The time course and the degree of recovery in the...

worldwide, more than 185,000 children under 18 years die from road traffic accidents annually (each four minutes a child death occurred due to road crashes); with most casualties from developing countries. 95% of road traffic fatalities among children occur in developing countries. many more children are injured, often severely, and suffering from different disabilities. road accidents cause ex...

Corticotropin-releasing factor (CRF) expressed in the hypothalamus plays an important role in mediating behavioral responses to stressors. Restraining the body of an animal has been shown to activate and induce an enhanced expression of CRF in paraventricular neurons of the rat hypothalamus. Since aggressive biting behavior is known to suppress stress-induced noradrenaline secretion in the cent...

The objectives of the study were to determine the most effective and reliable means of restraining children on an ambulance cot and to develop recommended field procedures for emergency medical service providers. A series of crash tests at 48 km/h were conducted using convertible child restraints, car beds, and harness systems tested with 3-year, infant, and 6-year size dummies. Belt configurat...

The design of the optimal child restraint environment must consider both vehicle system (VS) and child restraint system (CRS) components. The objective of this study was to analyze the contributions from each system using a computer simulation of a rear facing (RF) child restraint involved in frontal crash. A parametric study of the material characteristics of components in each system was perf...

background and aim : about one-third of iranian children mortality is caused by injuries from which 36% occur due to road traffic injuries. using child restraint embedded in vehicles can reduce road traffic fatalities by 71% for neonates and 54% for children. based on its effectiveness in reduction of fatality and prevention of injury severity, child restraint usage mandatory law is a priority....