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with the publication of the brundtland report carried the sustainability discussion into governments and businesses worldwide, much effort has gone into clarifying the meaning of the sustainability concept. to make the concept measurable and applied city sustainable idea, some new method was needed. so the method named ecological footprint has been presented.the ecological footprint method that...
today, scouring is one of the important topics in the river and coastal engineering so that the most destruction in the bridges is occurred due to this phenomenon. whereas the bridges are assumed as the most important connecting structures in the communications roads in the country and their importance is doubled while floodwater, thus exact design and maintenance thereof is very crucial. f...
That is the way Miriam Butt begins her book. Apparently, she felt that the quote fits her introduction to case theory within grammatical traditions (Latin grammar is one) and their relationship to various notions of case within modern theoretical linguistics. In her introduction to the book, Butt states “...several issues must be dealt with. One is the issue of what “case” really means and what...
Several reports in fly, nematode and mammalian cells have revealed that the inactivation of endosomal sorting complexes required for transport (ESCRT) blocks the endosomal maturation but also leads to the increased number of autophagosomal structures. In this review we compare these data and conclude that the way ESCRT mutations affect the relationships between autophagosomes and endosomes cann...
The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that catalyze multiple topologically similar membrane-remodeling processes. Although ESCRT-III subunits polymerize into spirals, how individual ESCRT-III subunits are activated and assembled together into a membrane-deforming filament remains unknown. Here, we determine X-ray crystal structures...
This paper describes an error detection mechanism which helps in validation of dependency treebank annotation. Consistency in treebank annotation is a must for making data as errorfree as possible and for assuring the usefulness of treebank. This work is aimed at ensuring this consistency and to make the task of validation cost effective by detecting major errors induced during completely manua...
Vps4 is a member of AAA+ ATPase (adenosine triphosphatase associated with diverse cellular activities) that operates as an oligomer to disassemble ESCRT-III (endosomal sorting complex required for transport III) filaments, thereby catalyzing the final step in multiple ESCRT-dependent membrane remodeling events. We used electron cryo-microscopy to visualize oligomers of a hydrolysis-deficient Vp...
This paper is a part of a wider research program concerning the assessment of quality at University. It was selected by the Department of University Policies (Ministry of Education, Science and Innovation) in an attempt to determine the causes and “reasons” underlying dropping school in our country. The Program includes three sub-projects concerning both academic and socio-professional success,...
Advanced live-cell imaging of the endosomal sorting complexes required for transport (ESCRT) and computational modeling have provided insights into the Vps4-dependent dynamic rearrangements of ESCRT-III filaments during membrane constriction and abscission.
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