A Chinese Herbal Formula (CHF) has acquired a certain therapeutic effect on chronic HBV infection. To assess the efficacy and safety of CHF on HBV replication in chronic HBV carriers, we performed a randomized, double-blind, and placebo-controlled trial involving patients from 16 centers. A total of 300 confirmed chronic HBV carriers were randomized at baseline in a ratio of 2 : 1 to receive ei...

a complication in the analysis of the role of icp34.5 gene in the herpes simplex virus type-1 (hsv-1) lifecycle is the presence of overlapping antisense gene, open reading frame p (orf p), which is also deleted in hsv-1 icp34.5 negative mutants. a hsv-1 wild type strain (17+) icp34.5/orf p deletion mutant (1716) is totally avirulent in animal models and impaired in a number of in vitro function...

By standardizing the management information base (MIB) for Ethernet and Token Ring LANs, a network administrator can use the management platform obtained from one vendor with RMON probes obtained from other vendors. Remote network monitoring (RMON) provides interoperability between network management products so that network administrators receive continuous feedback on activity on distant netw...

..................................................................................................................................8 2. REVIEW OF THE LITERATURE ...................................................................................... 13 2.1. HUMAN PAPILLOMAVIRUSES (HPVS) ........................................................................... 13 2.1.1. Genome and life cycle of H...

conclusions the results of this study indicated that the genes encoding aminoglycoside-modifying enzymes are prevalent in a. baumannii isolates in the study region, which highlighted the necessity of considering preventive measures to control dissemination of these resistance genes. results antimicrobial susceptibility analysis showed that the highest resistance was towards beta−lactam antibiot...

Pseudorabies virus (PRV), in the family Herpesviridae , is a pathogen of Aujeszky's disease, which causes great economic losses to pig industry. Recent outbreaks imply that new control measures are urgently needed. The present study shows kaempferol candidate drug for controlling PRV infection, as it possesses ability inhibit replication dose-dependent manner vitro . Kaempferol at concentration...

Hepatitis C virus (HCV) infection represents a major public health problem throughout the world. The establishment of viral replicons has enhanced our understanding of the mechanism underlying HCV replication. However, the specific virus-host cell interactions involved in HCV RNA replication are not well understood. In the present study, we isolated several human hepatoma Huh-7-derived subclone...

Mutations in the smu-1 gene of Caenorhabditis elegans were previously shown to suppress mutations in the genes mec-8 and unc-52. mec-8 encodes a putative RNA binding protein that affects the accumulation of specific alternatively spliced mRNA isoforms produced by unc-52 and other genes. unc-52 encodes a set of basement membrane proteins, homologs of mammalian perlecan, that are important for bo...