Background: Recurrent spontaneous abortion (RSA) and in vitro fertilization (IVF) failure with unknown causes are the controversial issues that are probably related to the immune system. Objective: To compare circulating NK cells expressing activation and inhibition surface markers between patients with RSA and IVF failure with those of healthy multiparous and successful IVF control women, resp...

This study sought to assess the efficacy of intravenous immunoglobulin (IVIg) in improving pregnancy rates and outcome, in a select group of patients with repeated IVF failure and human leukocyte antigen (HLA) similarity. Couples suffering from recurrent IVF failure, defined as at least seven attempts at embryo transfer with no successful implantations, who were found to share at least three HL...

objective: repeated implantation failure (rif) is a condition in which the embryos implantation decreases in the endometrium. so, our aim was to evaluate the effect of local endometrial injury on embryo transfer results. materials and methods: in this simple randomized clinical trial (rct), a total of 120 patients were selected. the participants were less than 40 years old, and they are in thei...

OBJECTIVE To establish a gas chromatography/mass spectrometry (GC/MS)-based metabolomics method to compare the metabolites in the follicular fluid (FF) from patients with in vitro fertilization (IVF) and repeated IVF failure (RIF). METHODS A prospective study was employed in Center for Reprodutive Medcine, Renji Hospital, Shanghai, China, between January and October 2010. FF samples were coll...

a:4:{s:10:"Background";s:363:"The largest percentage of failed in vitro fertilization (IVF) cycles are due to lack of implantation. As hereditary thrombophilia can cause in placentation failure, it may have a role in recurrent IVF failure. The aim of this case-control study was to determine whether or not hereditary thrombophilia is more prevalent in women with recurrent IVF failures.";s:19:"Ma...

Background: Because implantation failure is more frequent, many methods have been suggested to improve the implantation; however, their results have been inconsistent. One of the most hopeful methods is local endometrial injury. To explore the possibility that local injury of the endometrium increases the incidence of implantation and pregnancy rate in the subsequent IVF cycle in patients havin...

BACKGROUND The largest percentage of failed invitro fertilization (IVF (cycles, are due to lack of implantation. As hereditary thrombophilia can cause in placentation failure, it may have a role in recurrent IVF failure. OBJECTIVE Aim of this case-control study was to determine whether hereditary thrombophilia is more prevalent in women with recurrent IVF failures. MATERIALS AND METHODS Cas...

Retrieval of immature oocytes from unstimulated ovaries, followed by in vitro maturation (IVM) was originally proposed in order to avoid side effects of gonadotropin administration. The target is to eliminate or significantly reduce the risk of ovarian hyperstimulation syndrome (OHSS) in patients with polycystic ovary syndrome (PCOS), drug cost and burden on patients. This technology was also s...

background: repeated in vitro fertilization (ivf) failure together with ovarian hyperstimulation syndrome (ohss) is one of the distressing situations leading couples to search for alternative treatment options. for such patients with polycystic ovarian syndrome (pcos) who have experienced ovarian hyperstimulation syndrome, mild ovarian stimulation with in vitro oocyte maturation could be a prom...

Background: Clinical infertility is defined as the inability to become pregnant after 12 months of unprotected intercourse. Worldwide, more than 80 million couples suffer from infertility;the majority of this population are residents of developing countries. In vitro fertilization (IVF) is the most successful of the infertility treatments, and for many people is the last possibility for pregnan...