To determine whether expression of the renin-angiotensin system (RAS) is influenced by the degree of renal ablation, male Sprague-Dawley rats underwent uninephrectomy, 1 1/3 nephrectomy, or sham operation. Renin and angiotensinogen messenger RNA (mRNA) were not different among the three groups 2 weeks after surgery. The time course of expression of renin mRNA after 1 1/3 nephrectomy showed no d...

background and aim: urinary tract infections (uti) are common cause of morbidity and mortality especially in young children around the world. pyelonephritis can lead to scar formation, and subsequent hypertension and renal failure. interleukins play a major role in renal scar formation following febrile pyelonephritis. the aim of this study was to investigate the level of urinary interleukin-6 ...

INTRODUCTION Urinary tract infections (UTIs) are the most serious common bacterial infections among young children. It may affect kidneys that classified as acute pyelonephritis (APN) and may lead to renal parenchymal involvement and scarring with high prevalence rate (15%-60%) among children. This study aimed to assess the urinary concentration of neutrophil gelatinase-associated lipocalin (NG...

To cite: Sussman RD, Kowalczyk KJ. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218944 DESCRIPTION A middle-aged man with poor access to medical care presented with shortness of breath and 3 years of abdominal distention. On physical examination, he was found to have a palpable mass in the left upper quadrant. He was found to have undiagnosed congestive hea...

Background Detection of late gadolinium enhancement (LGE) is the method of choice for imaging myocardial scar. However, patients who suffer from cardiovascular disease often are afflicted with renal impairment. As a GFR <30 ml/min bears the risk of nephrogenic systemic fibrosis it would be beneficial to develop alternative cardiac imaging methods without contrast agent. De Jong et al have alrea...

Urinary tract infection (UTI) is a common bacterial illness in children. Acute pyelonephritis in children may lead to renal scarring with the risk of later hypertension, preeclampsia during pregnancy, proteinuria, and renal insufficiency. Until now, vesicoureteral reflux (VUR) has been considered the most important risk factor for post-UTI renal scar formation in children. VUR predisposes child...