Understanding the biology and genetic alterations of adipocytokines, cell-signaling proteins secreted by adipose tissue, provides new insights into the pathogenesis and treatment of several diseases including cancer. In the present study, we investigated the role of RETN gene G62A variant in the pathophysiology of colon cancer. A group of 120 Saudi volunteers (60-colon cancer patients and 60 di...

OBJECTIVE To investigate the relationship between lipoprotein lipase (LPL) gene polymorphism and cerebral hemorrhage in a Chinese population. METHOD This study was based on the case-control study, PCR-RELP and sequencing method were utilized for genotyping. LPL gene Hind III polymorphism was detected both in 300 patients with cerebral hemorrhage (CH group) and in 300 healthy control subjects ...

Nowadays, voice conversion is a problem which is intensively analyzed by many researchers. A large group of existing voice conversion systems is based on RELP re-synthesis. Within these systems, the speech signal is pitchsynchronously segmented and described with LSF parameters. A transformation function is acquired by employing pairs of equal time-aligned utterances from source and target spea...

OBJECTIVES To elucidate the gene frequency of TNFB Ncol polymorphism and its association with HLA class II antigen in patients with systemic lupus erythematosus(SLE) in Korea. METHODS We investigated the gene frequency of the TNFB alleles using DNA obtained from peripheral mononuclar cells in 141 healthy controls and in 58 patients with SLE. The polymorphisms of TNFB gene (735 bp) were studie...

AIM To investigate the association among XRCC1 polymorphisms, smoking, drinking and the risk of prostate cancer (PCa) in men from Han, Southern China. METHODS In a case-control study of 207 patients with PCa and 235 cancer-free controls, frequency-matched by age, we genotyped three XRCC1 polymorphisms (codons 194, 280 and 399) using the polymerase chain reaction-restriction fragment length po...

Reg IV (RELP), a Regenerating protein family member, is constitutively expressed in neuroendocrine cells of the intestinal mucosa. The helix-loop-helix transcription factor Hath1 is the human homologue of murine Math1, which regulates the embryonic differentiation of neural and intestinal secretory lineage cells. Hath1 is constitutively expressed in a subset of mature secretory gastrointestinal...

Bovine theileriosis is important disease in tropical and subtropical areas with great economic losses in livestock husbandry in Iran. The aim of study was to assess the prevalence of Theileria annulata infection in cattle and Hyalomma species of Kermanshah Province, Iran. A number of 138 blood samples were randomly taken from examined cattle. The genomic DNA was extracted and PCR was performed ...

The paper presents experiments on the use of the perceptual objective measure – ITU-T Rec. P.862 Perceptual Evaluation of Speech Quality (PESQ), for the automatic evaluation of synthetic speech. The approach is based on the evaluation of the statistically significant correlation between the outputs of subjective and objective tests. We propose the following technique to evaluate the usage of th...