The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. Various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

Objective(s): The quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. Aim of this study is to find out the isoniazid release kinetic. Methods: In this work degradable temperature sensitive dextran-hydroxy ethyl me...

The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. Various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

background: during the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. this is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. arginase competes with inducible nitric oxide synthase for a common substrate l-arginine. objective: to investigate whethe...

Guaifenesin, a highly water-soluble active (50 mg/mL), classified as a BCS class I drug.Owing to its poor flowability and compressibility, formulating tablets especially high-dose one,may be a challenge. Direct compression may not be feasible. Bilayer tablet technology appliedto Mucinex®, endures challenges to deliver a robust formulation. To overcome challengesinvolved in bilayer-tablet manufa...

objective(s): the quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. aim of this study is to find out the isoniazid release kinetic. methods: in this work degradable temperature sensitive dextran-hydroxy ethyl methacrylate- poly-n-isopropyl acryl amide (dex-hema-pnipaam) nan...

The purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. A 32 full factorial design was employed to study the effect of independent variables like Carbopol-934P and hydroxypropyl methylcellulose K100M, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...

Based on various characteristics of zeolite, its utilization in the manufacture of fertilizers with slow-release properties is possible. The objectives of this study are to characterize and utilized nitrogen, phosphorus and potassium (NPK) slow release fertilizer by using natural zeolite in Indonesia. In this research, zeolite was utilized as a mixture of Slow Release Fertilizer (SRF). Effect o...

microencapsulation has become a common technique in the production of controlled release dosage forms. many results have been reported, concerning the use of alginate beads as controlled release drug formulations. alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...