NMR relaxometry refers to the measurement of relaxation times (usually T1) as a function of magnetic field strength. It is usually accomplished using fast field-cycling (FFC), in which the magnetic field is switched rapidly between levels during the pulse sequence. By switching the magnetic field, the nuclear spins can “evolve” at a chosen magnetic field strength, after which the magnetic field...

BACKGROUND AND PURPOSE In mesial temporal lobe epilepsy, MR imaging quantification of hippocampal volume and T2 signal can improve the sensitivity for detecting hippocampal sclerosis. However, the current contributions of these analyses for the diagnosis of hippocampal sclerosis in 3T MRI are not clear. Our aim was to compare visual analysis, volumetry, and signal quantification of the hippocam...

The purpose of this study was to compare 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET), hippocampal volumetry (HV), T2 relaxometry, and proton magnetic resonance spectroscopic imaging (1H-MRSI) in the presurgical neuroimaging lateralization of patients with nonlesional, electroencephalogram (EEG)-defined unilateral temporal lobe epilepsy (TLE). Twenty-five patients were...

PURPOSE Heme and iron accumulation due to repeated hemorrhage in endometriosis may contribute to a pivotal role in carcinogenesis. We evaluate the clinical application of MR relaxometry in a series of ovarian endometriosis (OE) and endometriosis-associated ovarian cancer (EAOC). MATERIALS AND METHODS A prospective study of diagnostic accuracy was conducted among 82 patients (67 OE and 15 EAOC...

BACKGROUND AND PURPOSE FUS-induced BBB opening is a promising technique for noninvasive and local delivery of drugs into the brain. Here we propose the novel use of a neuronavigation system to guide the FUS-induced BBB opening procedure and investigate its feasibility in vivo in large animals. MATERIALS AND METHODS We developed an interface between the neuronavigator and FUS to allow guidance...

Background Current approaches to evaluate peripheral arterial disease (PAD) overwhelmingly rely on quantification of stenosis severity or flow across stenosis at rest. Although exerciseinduced functional alterations in metabolism have been proposed, there is a need to integrate approaches that provide additional risk measures in PAD that can be translated into clinical practice [1]. Recently, q...

To further investigate the effect of dilute acid pretreatment (DAP) and steam explosion pretreatment (SE) on the change in cellulose accessibility, several techniques were applied including a Simons' stain (SS) technique along with several NMR methods (i.e., NMR cryoporometry, (1)H spin-lattice (T1) and (1)H spin-spin (T2) relaxometry, and diffusometry). These methods were utilized to probe bio...