Journal:
:iranian journal of basic medical sciences
0
ali mohammadi karakani institute of biochemistry and biophysics, university of tehran, tehran, iran
gholamhossein riazi institute of biochemistry and biophysics, university of tehran, tehran, iran
seyed mahmood ghaffari institute of biochemistry and biophysics, university of tehran, tehran, iran
shahin ahmadian institute of biochemistry and biophysics, university of tehran, tehran, iran
farzad mokhtari institute of biochemistry and biophysics, university of tehran, tehran, iran
mahshad jalili firuzi institute of biochemistry and biophysics, university of tehran, tehran, iran
objective(s):alzheimer's disease (ad) is the most common age-related neurodegenerative disorder. one of the hallmarks of ad is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. in this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in ad and tauopathies. unfortunately, the available syn...