strongly positive for toxocariasis. Enzyme-linked immuno-sorbent assay for toxocaral antibodies showed 2.7 U (>1.1). Antinuclear, antineutrophil cytoplasmic antibodies, cryoglo-bulins and immune complexes were all negative. Computed tomography scans of the lungs, brain and abdomen were unremarkable. A bone marrow aspirate and biopsy revealed increased cell infiltration of the bone marrow with t...

End-stage renal disease (ESRD) patients have a dramatically higher risk of death compared with the general population [1]. In 1998, Block et al. showed that hyperphosphataemia and a high calcium phosphorus product are independently associated with mortality in dialysis patients [2]. More recently, based on a large cohort, the same authors have confirmed these findings adding hypercalcaemia and ...

OBJECTIVE Compare clinical outcomes and costs in a study group of long-term acute care hospital (LTCH) patients with a control group of LTCH-eligible patients in an acute care hospital. LTCHs were created to provide post-acute care services not available at other post-acute settings. This is based on the premise that these patients would otherwise have stayed at acute care hospitals as high-cos...

Dietary restriction (DR) extends lifespan in multiple species from various taxa. This effect can arise via two distinct but not mutually exclusive ways: a change in aging rate and/or vulnerability to the aging process (i.e. initial mortality rate). When DR affects vulnerability, this lowers mortality instantly, whereas a change in aging rate will gradually lower mortality risk over time. Unrave...

Human skin contains various populations of memory T cells in permanent residence and in transit. Arguably, the best characterized of the skin subsets are the CD8(+) permanently resident memory T cells (TRM) expressing the integrin subunit, CD103. In order to investigate the remaining skin T cells, we isolated skin-tropic (CLA(+)) helper T cells, regulatory T cells, and CD8(+) CD103(-) T cells f...