Chromaffin granule transmitters such as chromogranin A and catecholamines have been used in the diagnosis of pheochromocytoma, but the diagnostic and prognostic value of chromogranin A have not been explored in malignant pheochromocytoma. We evaluated these transmitters in patients with pheochromocytoma (n=27), both benign (n=13) and malignant (n=14). Patients with benign pheochromocytoma were ...

the intraoperative care of pheochromocytomas can be difficult and lead to serious complications. we present a case of a 46 year-old female undergoing laparoscopic resection of pheochromocytoma, who was scheduled for surgery with phenoxybenzamine and amlodipin. under general anesthesia cardiovascular stability was achieved by peritumoral infiltration of lidocaine during resection.

When a patient complaining of headache comes to the hospital, focus is usually on checking for neurological disorders. After these are excluded, functional headaches thought of, and it easy overlook other causes. In case presented here, was hospitalized with severe headache. There were no specific findings in either brain imaging or cerebrospinal fluid. The persisted, accompanied by excessive s...

Objective Pheochromocytoma and paraganglioma (PPGLs) are rare neuroendocrine tumors derived from the adrenal medulla or extra-adrenal paraganglioma from extra-adrenal chromaffin tissue. Although malignant PPGLs has miserable prognosis, the treatment strategy remains to be established. An internal radiation therapy using [131I]meta-iodobenzylguanidine (131I-mIBG) called MIBG therapy has been att...

there are few reported cases of endobronchial metastasis of pheochromocytoma literature. we present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. computed tomography showed a lobulated soft tissue mass, measuring, 38×27 mm, at the perivascular space of anterior mediastinum. the resected specimen, showed lobulated tumo...

the distinction between malignant and benign pheochromocytoma has always been a diagnostic challenge over the last decades. to date, the only reliable criterion is metastasis. the aim of the present study was to investigate the possible expression of pituitary-tumor transforming gene (pttg1) and retinoblastoma (rb) in benign and malignant pheochromocytoma. paraffin blocks of 44 and 11 patients ...

One of the rarest tumors involving the urinary bladder is the pheochromocytoma. A case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. Twenty-four hour urine VMA was normal. The patient was never hypertensive except during surgical manipulation of the tumor. Biopsy of the bladder resulted in massive hemorrhage.

Paragangliomas/pheochromocytomas are uncommon neuroendocrine tumors that arise from chromaffin cells located outside of the adrenal gland. Although cardiac paragangliomas have been observed in all heart chambers, most prevalent left-atrial paragangliomas, followed by aortic body tumors. Diagnosis paragangliomas/pheochromocytomas is mostly achieved with a multimodality approach because her clini...

one of the rarest tumors involving the urinary bladder is the pheochromocytoma. a case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. twenty-four hour urine vma was normal. the patient was never hypertensive except during surgical manipulation of the tumor. biopsy of the bladder resulted in massive hemorrhage.