The most common extraesophageal manifestations of gastroesophageal reflux disease (GERD) include chronic cough, asthma and laryngitis. There are two mechanisms proposed to explain extraesophageal syndromes caused by GERD. The first one is a direct way via irritation and/or microaspiration and the second one is an indirect, vagally mediated way. The investigation of extraesophageal manifestation...

BACKGROUND Asthma, laryngitis and chronic cough are atypical symptoms of the gastroesophageal reflux disease. AIM To analyze the efficacy of laparoscopic surgery in the remission of extra-esophageal symptoms in patients with gastroesophageal reflux, related to asthma. METHODS Were reviewed the medical records of 400 patients with gastroesophageal reflux disease submitted to laparoscopic Nis...

OBJECTIVES/HYPOTHESIS A literature review regarding the use of laryngopharyngeal mucosal signs in diagnosing laryngopharyngeal reflux (LPR). STUDY DESIGN Literature review. METHODS A search of MEDLINE in February 2012 using the terms laryngopharyngeal reflux, laryngitis, mucosa, appearances, and signs (English language only). RESULTS One or more laryngopharyngeal mucosal signs associated ...

etry. Many patients also present chronic posterior laryngitis in fibronasolaryngoscopy (FNL). The objective of the present study was to evaluate the diagnosis of esophagitis, by FNL and UGE in patients with chronic cough. Methods: Patients followed up for chronic cough, over 18 years of age, were asked about the presence of GERD symptoms and submitted to the FNL and UGE, some of them with esoph...

Gastroesophageal reflux disease often presents as heartburn and acid reflux, the so-called "typical" symptoms. However, a subgroup of patients presents a collection of signs and symptoms that are not directly related to esophageal damage. These are known collectively as the extraesophageal manifestations of gastroesophageal reflux disease. Principal among such manifestations are bronchospasm, c...

etry. Many patients also present chronic posterior laryngitis in fibronasolaryngoscopy (FNL). The objective of the present study was to evaluate the diagnosis of esophagitis, by FNL and UGE in patients with chronic cough. Methods: Patients followed up for chronic cough, over 18 years of age, were asked about the presence of GERD symptoms and submitted to the FNL and UGE, some of them with esoph...