The role of dynamic instabilities in the initiation of reentry in diseased (remodeled) hearts remains poorly explored. Using computer simulations, we studied the effects of altered Na(+) channel and cell coupling properties on the vulnerable window (VW) for reentry in simulated two-dimensional cardiac tissue with and without dynamic instabilities. We related the VW for reentry to effects on con...

BACKGROUND Functional reentry in the heart takes the form of spiral waves. Drifting spiral waves can become pinned to anatomic obstacles and thus attain stability and persistence. Lidocaine is an antiarrhythmic agent commonly used to treat ventricular tachycardia clinically. We examined the ability of small obstacles to anchor spiral waves and the effect of lidocaine on their attachment. METH...

This study describes factors that contribute to spontaneous termination of reentry lasting one to 10 cycles after induction by a single premature stimulus. Reentry was studied in vitro in rings of canine atrial tissue from around the tricuspid valve orifice. Activation was recorded from a circular array of 10 extracellular bipolar electrodes equally spaced around the ring. In some experiments, ...

conclusions echocardiography and 2d speckle tracking strain imaging shows improvements in left ventricular deformation indices in atrioventricular reentrant tachycardia (avrt) and atrioventricular nodal reentrant tachycardia (avnrt) patients for the mean systolic strain and strain rate at 24 hours and the three-month follow-up. in spite of the normal lvef, even during sinus rhythm, deformation ...

Introduction: Ablation of Atrial Fibrillation (AF) can induce several types of Atrial Tachycardias (ATs). Perimitral reentry is a common mechanism among postablation ATs. The electrocardiographic (ECG) criteria for differentiating perimitral reentry from other postablation ATs may be useful in clinical practice. Methods and results: A total of 48 consecutive post atrial fibrillation ablation pa...

it has been well - established that common atrial flutter is due to intraatrial macroreentry and its reentry circuit locates in the right atrium. this reentry circuit has been characterized to involve an area of slow conduction identifiable electrophysiologically at the low posteroseptal right atrium and anatomical narrow isthmus snrrounded by the inferior vena capa, coronary sinus astium and t...

The purpose of this paper is to examine the multidisciplinary design optimization (MDO) of a reentry vehicle. In this paper, optimization of a RV based on, minimization of heat flux integral and minimization of axial force coefficient integral and maximization of static margin integral along reentry trajectory is carried out. The classic optimization methods are not applicable here due to the c...

IIIDuring the period from June 1958 through September 1965 Lincoln Laboratory engaged in a reentry measurements program that developed radar and optical instrumentation for observing the phenomena associated with the hypervelocity reentry ofpayloads into the earth's atmosphere. This article describes both the Lincoln Laboratory effort and the development and launching of reentry test vehicles b...