نتایج جستجو برای: reductive amination
تعداد نتایج: 11636 فیلتر نتایج به سال:
Functionalized chiral tetrahydroquinolines were synthesized through supramolecular organocatalysis using quinidine-NH-thiourea 3c/L-phenylalanine 4i followed by reductive amination from the simple substrates.
9-Aminononanoic acid, 9-aminononanamide, and related compounds derived from soybean oil by reactions, including reductive ozonolysis and reductive amination, were separated on an analytical scale either by gas liquid chromatography of trifluoroacetylated or trimethylsilylated derivatives or by thin layer chromatography and on a preparative scale by ion-exchange chromatography. Comparative analy...
Amines are the most important building blocks employed in modern medicinal chemistry. Secondary amines are regularly prepared by the alkylation or reductive amination of the parent amines through transition metal, typically precious metals, catalyzed reactions. In the past few years, the catalytic alkylation of amines with alcohols under hydrogenborrowing conditions as well as the catalytic red...
Highly purified preparations of glutamate synthase catalyze the TPNH-dependent reductive amination of cu-ketoglutarate to form L-glutamate in the presence of either L-glutamine or NH:,. Preparations of the enzyme that lack flavins (FAD and FMN) or the flavins and iron sulfide, catalyzed NH,,-mediated glutamate synthesis, but not glutamine-mediated glutamate synthesis. Participation of enzyme-fl...
Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.
Sodium triacetoxyborohydride is presented as a general reducing agent for the reductive amination of aldehydes and ketones. Procedures for using this mild and selective reagent have been developed for a wide variety of substrates. The scope of the reaction includes aliphatic acyclic and cyclic ketones, aliphatic and aromatic aldehydes, and primary and secondary amines including a variety of wea...
Individuals with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) induced by high calorie western diet are characterized by enhanced lipogenesis and gluconeogenesis in the liver. Stimulation of reductive amination may shift tricarboxylic acid cycle metabolism for lipogenesis and gluconeogenesis toward glutamate synthesis with increase of NAD+/NADH ratio and thus, ameliorate h...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید