introduction although thymoma is the most common anterior mediastinal tumor, only 5% of thymoma cases develop pure red cell aplasia (prca). case presentation in this article we have reported a 59-year-old man with a large anterior mediastinal mass (diameter of 10 cm) and severe anemia, that thymoma and pure red cell aplasia have been demonstrated by histopathologic and hematological examination...

results it was found that in all studied wavelengths with or without methylene blue (mb), the level of all studied enzymes decreased remarkably when compared to dark controls. it was observed that the synthesis level of sod, glutathione peroxidase gp, and glucose 6 phosphate dehydrogenase g-6-pd in e. coli decreased significantly in red light with respect to white, blue, and green light in seaw...

AIMS/BACKGROUND Oxidative damage has been proposed to be involved in the pathogenesis of age-related macular degeneration (ARMD). The purpose of this study was to evaluate whether red blood cell antioxidant enzyme activity correlates with severity of aging maculopathy in affected individuals. METHODS Blood samples were obtained from 54 patients with varying severity of aging maculopathy and 1...

The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which proceeds through the Embden-Meyerhof pathway to pyruvate with production of ATP (fig 1). Some of the...

Red cell enzyme activity was m easured in packed red cells obtained from spun hematocrit tubes and compared with results obtained using standard methods (washed, filtered, red blood cells [WFRBC]) in order to evaluate the feasibility of using heel puncture as a means of obtaining accurate quantitative red cell enzym e data in the new born period. Glucose-6phosphate dehydrogenase (G-6-PD) and py...

The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which proceeds through the Embden-Meyerhof pathway to pyruvate with production of ATP (fig 1). Some of the...

background: to investigate the association between the red cell distribution width (rdw) and mortality in patients with acute pancreatitis (ap), and to assess the ability of rdw to predict mortality in ap patients. materials and methods: this retrospective cohort study included 120 patients (50 males and 70 females) with ap who were admitted to the first affiliated hospital of zhongshan medical...

although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. we only found one case in literature reviews. we report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. with a mediastinotomy incision, biopsy of the tumor was obtained. the report of the pathologist was thy...

background: asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. the present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (nrbc) cells, for early diagnosis of perinatal asphyxia. objective: in this study, we evaluated the mean nr...

Previous studies have shown a marked effect of very high levels of copper on red cell glucose-6-phosphate dehydrogenase and glutathione. When the effect of more nearly physiological levels of copper were studied, red cell hexokinase, phosphofructokinase, phosphoglyceric kinase, pyruvate kinase, and 6-phosphogluconate dehydrogenase were found to be inhibited. Inhibition was observed both when co...