Focal coronary spasm is often associated with an area of mural plaque disease. This report describes a patient with recurrent severe coronary spasm unresponsive to medical treatment. Coronary arteriography and intravascular ultrasound identified a candidate area of minor coronary atheromatous disease but ergonovine provocation testing showed the spastic coronary segment to be distal to and dist...

BACKGROUND Several clinical risk estimation tools have established their role in the prediction of recurrence of acute coronary syndrome (ACS), but the value of genetic risk scores (GRSs) remains unclear. We examined how well 2 different GRSs estimate recurrent ACS and whether clinical factors are associated with GRSs. METHODS AND RESULTS A cohort of 2090 consecutive patients with ACS who und...

BACKGROUND Although depression is a well-documented risk factor for clinical heart disease, its association with subclinical atherosclerosis is unclear. We hypothesized that middle-aged women with a history of recurrent major depression would show evidence of atherosclerosis. METHODS Coronary and aortic calcification was measured by electron beam tomography in 58 African American and 152 whit...

Kawasaki disease is very rare in Western Europe. The disease may involve coronary arteries. A 2-year-old boy diagnosed with Kawasaki disease had had seizure-like symptoms. Further evaluation revealed recurrent myocardial ischemia and myocardial infarction. Due to extraordinary extension of the coronary disease, myocardial revascularization was not feasible and the toddler underwent successful h...

background: the existing evidence suggests that plasma adiponectin concentrations can be indicative of the presence and severity of coronary artery disease (cad). however, the results of the studies conducted hitherto on this subject are inconsistent. we sought to investigate the possible correlation between plasma adiponectin levels and the presence and severity of cad in patients undergoing n...

background and objective: obstructive sleep apnea (osa) is frequent and in some degree it affects about 24% of male and 9% of female in middle age adults. this study aimed to assess the association between risk of osa and cad. materials and methods : this case-control study was performed among 184 patients with a history of coro- nary angiography in two catheter labs at hospitals in qom, iran. ...

inflammatory basis in pathopoiesis of coronary artery disease (cad) have been demonstrated in recent decades. elevated c-reactive protein (crp) and leukocytosis were associated with an elevated risk   for acute coronary syndrome (acs). to evaluate the relationship between quantitative crp and cardiac troponin i in conjunction with white blood cell (wbc) count and 30 days outcomes and treatment ...

background: coronary angiography, albeit a safe procedure, may cause serious complications especially in patients with left main stenosis (lms). this study was designed to investigate the efficacy of workload achieved by exercise tolerance test (ett) in predicting lms in candidates for coronary angiography. methods: a total of 743 patients with a positive ett who subsequently underwent cardiac ...