¿Debemos olvidar la rectosigmoidoscopia para el diagnóstico de neoplasia avanzada colorrectal? There is a rising trend in colorectal cancer worldwide and despite the advances in medicine and the fact that the important risk factors of age above 50 years, male sex, a family history of the disease, smoking, obesity, and diabetes mellitus are recognized, it has not been possible to determine a fac...

Sir, With reference to the article by Novella-Maestre et al. (2009) on the experimental treatment of endometriosis with cabergoline (Cb2), the authors suggested that Cb2 manifests its anti-angiogenic effect by acting via VEGFR-2. A case which we recently encountered seems to support this hypothesis. A 36-year-old woman presented in September 2008 with complaints of abdominal, lower back and pel...

Background and study aims  Rectosigmoidoscopy with biopsy has been regarded to be a useful procedure to diagnose gastrointestinal graft-versus-host disease (GVHD). However, little is known about the specific colonoscopic features of gastrointestinal GVHD. In this study, we focused on the 4 unique colonoscopic findings - orange peel appearance, spotty redness, small mucosal sloughing, and diffus...

Patients will typically present symptoms of chronic post-radiation colitis and proctitis 8–12 months after finishing their treatment. Endoscopic methods play the main role treatment bleeding caused by proctitis. Surgical is required for remained approximately 10% patients. Here we a 64 year old female with metastatic breast cancer, who was referred to us intractable rectal bleeding. Total colon...

AIM To evaluate the effectiveness of metronidazole in combination with corticosteroids in enema and mesalazine (5-aminosalicylic acid) in comparison with the same protocol without metronidazole in the treatment of chronic radiation proctitis. METHODS Sixty patients with rectal bleeding and diarrhea were randomly divided into two groups. Patients in the first group were treated with metronidaz...

UNLABELLED Screening of the colon cancer seems to be important to improve the results of the surgical treatment. There are different screening programs, the most common use the fecal occult blood (FOB) tests or colonoscopy. THE AIM OF THE STUDY was to evaluate the results of the colon cancer screening based on the FOB test and perform the algorhytm improving the effectiveness of the screening...

PURPOSE We assessed the value of dose-volumetric parameters predicting rectosigmoid mucosal changes (RMC) and late rectosigmoid complications (LRC). METHODS Between January 2004 and February 2006, 77 patients with stage IB-IIIB cervical cancer underwent external beam radiotherapy and computed tomography (CT)-based intracavitary irradiation. Total dose to the rectal point and several dose-volu...

Case report Here we report for the first time two patients with MKD revealed by a severe neonatal colitis. Both patients had chronic bloody diarrhea and failure to thrive, one patient since the age of one month and the other twelve days. Total parenteral nutrition was required. A marked elevation of acute phase reactants was present, and no evidence of infection was found. In patient 1, ileocol...

A 15-year-old boy presenting blood in stools for one month. Four days after the symptoms onset, the patient underwent rectosigmoidoscopy which revealed the presence of stale blood in the rectosigmoid junction. Serum hemoglobin level was 11 mg/dl. History of appendectomy three years before. At color Doppler US, a fixed cystic image with gut signature was observed in the right lower abdominal qua...