BACKGROUND Severe skin rash as toxicity of erlotinib has been reported in relation to better response and survival. However, some patients require dose reduction due to skin toxicities, and their prognosis remains uncertain. We retrospectively evaluated the clinical course of non-small cell lung cancer patients receiving erlotinib at a reduced dose because of skin rash. PATIENTS AND METHODS A...

conclusions: patients who were given ketamine before or after cesarean section subcutaneously at incision site had lower pain intensity and less analgesic consumption than patients who were given placebo. patients and methods: sixty patients, aged between 18 and 25 years old, scheduled for elective cesarean section, were enrolled to this double-blind randomized controlled trial study. patients ...

Introduction: In brachytherapy treatments, high-dose sources are used in interstitial placement. In this paper, the modeling of a common breast cancer treatment applicator called MammoSite is done by the Monte Carlo simulation code. Then, to study and calculate the amount of doses in the breast and the dose rate of the organs at risk of radiation, including: lungs, ribs and ski...

PURPOSE Skin is a major organ at risk in breast-conserving therapy (BCT). The American Brachytherapy Society (ABS) recommendations require monitoring of maximum dose received, however, there is no unambiguous way of skin contouring provided. The purpose of this study was to compare the doses received by the skin in different models. MATERIAL AND METHODS Standard treatment plans of 20 patients...

background this study investigated the anti-inflammatory effect of fumaria parviflora due to its fumaric acid, flavonoid and phenolic compounds for skin diseases, relieves itching and eczema. material and methods male wistar rats (ranging 150-180g in weight) were used. for preparation of the hydro alcoholic extract, plant powdered were macerated in ethanol 70%, then extract were concentrated fo...

background and objective: the most common intravascular brachytherapy sources include 32p, 188re, 106rh and 90sr/90y. in this research, skin absorbed dose for different covering materials in dealing with these sources were evaluated and the best covering material for skin protection and reduction of absorbed dose by radiation staff was recognized and recommended. method: four materials includin...

PURPOSE/OBJECTIVES To determine the prevalence of and risk factors for maculopapular skin rashes associated with high-dose chemotherapy. DESIGN Observational pilot study. SETTING A bone marrow transplant hematology-oncology unit in a private city hospital. SAMPLE Data were collected on 14 patients who developed maculopapular rashes out of 127 patients who received high-dose chemotherapy (...

Background: To date, different kinds of treatment methods have been proposed for radiotherapy of cancer patients. Choosing the kind of treatment method affects the quality of the patient's treatment. This study aims to investigate the effect of the number of radiation treatment sessions on the dose received by the patient and the distribution of tumor dose and dose received by organs at risk in...

Introduction The increasing practice of interventional fluoroscopy in diagnosis and treatment of cardiovascular disease has risen attention to improve radiation protection of patients and cardiologists in these relatively high dose techniques. Therefore, nowadays there is an emphasis on the measurement of radiation dose received by patients and cardiologists arising from the relevant procedures...

introduction accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction materials and methods electron contamination in prostate radiotherapy was investigated using the monte carlo (mc) code calculation. in addition, field size dependence of the skin dose was assessed. excess cancer risk induced by...