The present study was carried out to evaluate the role of apoptotic proteins in REC-2006-mediated radiation protection in hepatoma cell lines. REC-2006 treatment 2 h before irradiation strongly inhibited the cleavage of ATM and PARP-1 in HepG2 cells. The expression of nuclear apoptosis inducing factor (AIF) was found to be more inhibited (~17%) in HepG2 cells in REC-2006 + radiation-treated gro...

OBJECTIVES To evaluate user satisfaction among practices receiving services provided by the Arizona Regional Extension Center (REC). METHODS This program evaluation utilized a mixed-methods approach including: 1) a mail-based survey targeting all 489 REC member practices; and 2) a series of telephone-based focus groups using a convenience sample of rural and urban REC member practices. Target...

The uvr mutations of Escherichia coli K-12 decrease the ability of cells to survive ultraviolet light (UV), to excise pyrimidine dimers from their deoxyribonucleic acid and to reactivate bacteriophage exposed to UV. The rec mutations decrease the ability of the cells to survive UV and to undergo genetic recombination. Certain rec mutations, including recA1, rec-12, recA13, and rec-56, are neces...

Twenty ASA physical status Class III patients undergoing cadaver renal transplantation were studied. After 90 per cent T1 recovery, as determined by train-of-four measurement, from 1.0 mg.kg-1 succinylcholine to facilitate tracheal intubation, nine patients received atracurium 0.25 mg.kg-1 (Group I) and 11 patients received vecuronium 0.05 mg.kg-1 (Group II) intravenously. The following measure...

The pharmacological properties of cyclohexanecarboxylic acid, {2-[4-(2-bromo-5-methoxybenzyl)piperazin-1-yl]ethyl}-(2-trifluoromethoxyphenyl)amide (Rec 27/0224), and cyclohexanecarboxylic acid, (2-methoxy-phenyl)-{2-[4-(2-methoxyphenyl)-piperazin-1-yl]ethyl}amide (Rec 27/0074), were characterized using radioligand displacement and guanosine 5'-O-(3-[35S]thiotriphosphate) ([35S]GTPgammaS) bindin...

Abstract Let $A \subseteq \{0,1\}^n$ be a set of size $2^{n-1}$ , and let $\phi \,:\, \{0,1\}^{n-1} \to A$ bijection. We define the average stretch $\phi$ as \begin{equation*} {\sf avgStretch}(\phi ) = {\mathbb E}[{{\sf dist}}(\phi (x),\phi (x'))], \end{equation*} where expectation is taken over uniformly random $x,x' \in \{0,1\}^{n-1}$ that differ in exactly one coordinate. In this paper, we c...

ENES affecting the frequency of recombination between allelic differences have been found in Neurospora crassa (JESSOP and D. G. CATCHESIDE 1965; D. G. CATCHESIDE 1966; JHA 1967). In the two most extensively studied cases, crosses homozygous for rec (a general symbol for genes affecting recombination) exhibit allelic recombination frequencies an order of magnitude or more greater than those con...