To improve the efficiency of reliability-centered maintenance (RCM) analysis, case-based reasoning (CBR), as a kind of artificial intelligence (AI) technology, was successfully introduced into RCM analysis process, and a framework for intelligent RCM analysis (IRCMA) was studied. The idea for IRCMA is based on the fact that the historical records of RCM analysis on similar items can be referenc...

Kinsey GR, McHowat J, Beckett CS, Schnellmann RG. Identification of calcium-independent phospholipase A2 in mitochondria and its role in mitochondrial oxidative stress. Am J Physiol Renal Physiol 292: F853–F860, 2007. First published October 17, 2006; doi:10.1152/ajprenal.00318.2006.—Oxidant-induced lipid peroxidation and cell death mediate pathologies associated with ischemiareperfusion and in...

Oxidant-induced lipid peroxidation and cell death mediate pathologies associated with ischemia-reperfusion and inflammation. Our previous work in rabbit renal proximal tubular cells (RPTC) demonstrated that inhibition of Ca(2+)-independent phospholipase A(2) (iPLA(2)) potentiates oxidant-induced lipid peroxidation and necrosis, implicating iPLA(2) in phospholipid repair. This study was conducte...

We present the novel Random-Cluster Model (RCM), a time-variant frequency-selective MIMO channel model. The most significant feature of the RCM is that it is parametrised directly from channel measurements by an automatic procedure. Thus, the RCM is specific to the environment, although it retains all advantages of a stochastic model. In this way it closes the gap between channel measurements a...

OBJECTIVE To analyze dermoscopically identified streaks by direct correlation with features visualized on reflectance confocal microscopy (RCM). DESIGN We evaluated by RCM melanocytic lesions showing peripheral streaks on dermoscopy. A digital camera connected to the RCM computer enabled direct analysis of the streaks. The lesions were excised and histopathologically analyzed. SETTING Derma...

BACKGROUND AND OBJECTIVE In vivo reflectance confocal microscopy (RCM) is a promising novel technology for non-invasive early diagnostics of cutaneous melanoma. However, the possibility to detect melanocytic atypia in nevi by means of in vivo RCM remains unknown. The aim of the study was to evaluate the significance of in vivo RCM features of melanocytic atypia for the diagnosis of melanocytic ...

OBJECTIVE To determine the utility of reflectance confocal microscopy (RCM) in the in vivo evaluation of dermoscopic structures of melanocytic lesions. DESIGN For each described dermoscopic feature, we evaluated by RCM at least 2 melanocytic lesions. A digital camera connected to the confocal computer enabled direct analysis of the dermoscopic structures. To ascertain precision of correlation...

Biopsy and histologic evaluation have been the gold standard to diagnose skin tumors. Reflectance confocal microcopy (RCM) is a noninvasive, innovative diagnostic technique that enables visualization of different skin layers at an almost histologic resolution. RCM has been proven beneficial in management of various cutaneous lesions. This article highlights the clinical significance and future ...

BACKGROUND In vivo reflectance confocal microscopy (RCM) is a novel non-invasive diagnostic tool, which is used to differentiate skin lesions. Even in lesions with similar dermatoscopic images, RCM may improve diagnostic accuracy. METHODS Three sets of false "twin lesions" with similar macroscopic and dermatoscopic images are matched. All lesions are evaluated with RCM and lesions are excised...

In the RCM reactions of a series of simple α,ω-dienes, the relative order of reactivity has been unambiguously determined showing that cyclohexene forms faster than cyclopentene or cycloheptene. 1,5-Hexadiene inhibits the RCM of 1,7-octadiene; 1,5-hexadiene cannot progress to the RCM product (cyclobutene) but forms an unexpectedly stable cyclic η(2)-complex.