The pressure-rate product during anginal pain produced by right atrial pacing was studied in 12 patients before, during, and after an angiotensin infusion sufficient to produce a significant rise in blood pressure. During the infusion the pain occurred at a significantly lower heart rate (P less than 0.001). However, the pressure-rate product was similar during anginal pain before and during th...

BACKGROUND Laryngoscopy and intubation increases blood pressure and heart rate. OBJECTIVE The study aims to investigate the effect and safety of gabapentin, esmolol or their combination on the haemodynamic response to laryngoscopy and intubation. METHODS A total of 72 patients undergoing elective surgery were randomly allocated to one of the four groups. First study drug was administered or...

Symptom-limited maximal oxygen intake (VO SL) and electrocardiographic responses to multistage treadmill test were determined before and after 3 months of physical training in 14 patients with coronary heart disease. Six patients also had hemodynamic studies done at several submaximal work loads in the upright position before and after training. S-T-segment responses were measured by computer a...

Neither stroke volume nor external cardiac work (the integral of pressure times flow during ejection) has been considered an important correlate of myocardial oxygen consumption. An initial set of experiments re-examined this question of independently varying heart rate, systolic blood pressure, and stroke volume in seven closed-chest, anesthetized dogs. This was achieved by cardiac pacing, a p...