starch could used as ingredient fillers, binders and crushers in tablet manufacture. Amylum is also defined carbohydrates from plant, results photosynthesis, which stored part certain plant backup food mixture two type structure different polysaccharides that contains (17-20) % amylose (80-83) amylopectin. Destination study this for know the formulation of mucoadhesive tablets with fully gelati...

research advances during recent years offer new insight into therapy and the prevention of gastrointestinal ulcers by using medicinal plants. flavonoids, tannins, triterpenoids, fatty acids and essential oils are among the most effective herbal constituents that have potential antiulcerogenic properties, and most of them could be found in zataria multiflora. z. multiflora is one of the indigeno...

Shuidouchi (Natto) is a fermented soy product showing in vivo gastric injury preventive effects. The treatment effects of Shuidouchi fermented in different vessels on HCl/ethanol-induced gastric mucosal injury mice through their antioxidant effect was determined. Shuidouchi contained isoflavones (daidzein and genistein), and GVFS (glass vessel fermented Shuidouchi) had the highest isoflavone le...

Mucus thickness is suggested to be related to mucosal protection. We therefore investigated the importance of the removable mucous layer and epithelial bicarbonate transport in preservation of the gastric juxtamucosal pH (pH(jm)) during luminal acid. Anesthetized rats were prepared for intravital microscopy of the gastric mucosa, and pH(jm) was measured with pH-sensitive microelectrodes. The mu...

BACKGROUND Ranitidine is a histamine 2 receptor antagonist, and daijokito is a Kampo (Chinese herbal medicine as practiced in Japan) formula, which is traditionally used for treating constipation and digestive trouble. Previous study demonstrated that daijokito significantly affected the pharmacokinetics of ranitidine in rats; however, the doses of ranitidine and daijokito in that study were hi...

The aim of this study was to determine if taste interactions occur when bitter stimuli are mixed. Eight bitter stimuli were employed: Denatonium benzoate (DB), (L-phe), Ranitidine-HCl, and Tetralone®. The first experiment constructed individual psychophysical curves for each subject (n=19) for each compound to account for individual differences in sensitivities when presenting bitter compounds ...

OBJECTIVE To evaluate the possible antiulcer effect of the African garden egg, Solanum aethiopicum (S. aethiopicum) (a domestic vegetable) experimentally in rats. METHODS A methanol extract of the plant fruit was prepared by maceration. Twenty five overnight fasted rats for each model were divided randomly into five groups of five rats. Groups 1, 2, 3, 4 and 5 received normal saline, extract ...

The role of oxygen derived free radicals in gastric lesions induced by haemorrhagic shock and the protective effect of oxygen radical scavengers, allopurinol and ranitidine, were investigated. Forty five rabbits underwent haemorrhagic shock for 30 minutes and reinfusion of shed blood. They were killed 30 minutes later. The animals were divided in five groups: A (n = 10): Control, B (n = 10): in...